Content of research
Based on chemical proteomic approaches, our research interests are focused on the rational design and synthesis of small organic compounds that potentially modulate protein-protein interactions. These compounds are also utilized as a tool in our chemical genomic study to elucidate intracellular signaling pathways.
Current Research Programs
- 1. Drug discovery based on controlling intracellular signal transductions by small molecues.
- 2. Design and synthesis of inhibitors for bacterial efflux pumps.
- 3. Design and synthesis of bioactive lipids as probe molecues for chemical biology and development of the lipid transport acivity monioring system.
Figure / Graph
Anti-cancer agents based on natural diterpene glycosides
Identification of virus genome using novel type of nucleobases