Specially Appointed Assoc. Prof.
Content of research
Based on chemical proteomic approaches, our research interests are focused on the rational design and synthesis of small organic compounds that potentially modulate/inhibit protein-protein interactions. These compounds are also utilized as a tool in our chemical genomic study to elucidate intracellular signaling pathways. Our research also extends into the development of a novel type of nucleobase that can specifically recognize virus genome sequence.
Current Research Programs
- 1. Drug discovery based on controlling intracellular signal transductions by low-molecular-weight compounds.
- 2. Exploring new methodologies for efficient supply of biologically-active natural products in combination of total synthesis and biosynthesis.
- 3. Sequence specific detection of virus genome by novel type of nucleobases.
- 4. Design and synthesis of inhibitors for bacterial efflux pumps.
Figure / Graph
Anti-cancer agents based on natural diterpene glycosides
Identification of virus genome using novel type of nucleobases