Publications

2024

Original Paper

1. Selective Recognition between Aromatics and Aliphatics by Cage-Shaped Borates Supported by Machine Learning Approach

Tsutsui, Y.; Yanaka, I.; Takeda, K.; Kondo, M.; Takizawa, S.; Kojima, R.; Konishi, A.; Yasuda, M. Org. Biomol. Chem. 2024, in press (DOI).

2. In-Silico-Assisted Derivatization of Triarylboranes for the Catalytic Reductive Functionalization of Aniline-Derived Amino Acids and Peptides with H₂

Hisata, Y.; Washio, T.; Takizawa, S.; Ogoshi, S.; Hoshimoto, Y. Nat. Commun. 2024, in press.

3. Product Selectivity Control under Acidic and Basic Conditions on Oxidative Transformation of 1,3-Dicarbonyls Using Sodium Hypochlorite Pentahydrate

Kirihara, M.; Sakamoto, Y.; Tanaka, T.; Kawai, T.; Okada, T.; Kimura, Y.; Takizawa, S. Synthesis 2024, 56, in press (DOI)

4. Synthesis and Structural and Optical Behavior of Dehydrohelicene-Containing Polycyclic Compounds

Khalid, Md. I.; Salem, M. S. H.; Takizawa, S. Molecules 2024, 29, 296 (DOI).

5. Light-induced autoxidation of aldehydes to peracids and carboxylic acids

Salem, M. S. H.; Dubois, C.; Takamura, Y.; Kitajima, A.; Kawai, T.; Takizawa, S.; Kirihara, M. Green Chem. 2024, 26, 375 (DOI).

2023

Original Paper

1. Electrochemical Carbon-Ferrier Rearrangement Using a Microflow Reactor and Machine Learning-assisted Exploration of Suitable Conditions

Sato, E.; Tachiwaki, G.; Fujii, M.; Mitsudo, K.; Washio, T.; Takizawa, S.; Suga, S. Org. Process Res. Dev. 2023, in press (DOI).

2. Data-driven Electrochemical One-pot Synthesis of Double Hetero[7]dehydrohelicene

Salem, M. S. H.; Sharma, R.; Khalid, Md. I.; Sasi, M.; Amasaki, R.; Imai, Y.; Arisawa, M.; Takizawa S. Electrochemistry 2023, 91, 112015 (DOI).

3. Antifouling Brominated Diterpenoids from Japanese Marine Red Alga Laurencia venusta Yamada

Fukada, R.; Yamagishi, Y.; Nagasaka, M.; Osada, D.; Nimura, K.; Oshima, I.; Tsujimoto, K.; Kirihara, M.; Takizawa,　S.; Kikuchi, N.; Ishii, T.; Kamada, T. Chem. Biodiversity 2023, 20, e202300888 (DOI).

4. Azobenzene─based Chiral Photoswitchable Catalysts

Kondo, M.; Nakamura, K.; Sasai, H.; Takizawa, S. J. Synth. Org. Chem. Jpn. 2023, 81, 817 (DOI).

5. Light-controlled pKa Value of Chiral Brønsted Acid Catalysts in Enantioselective Aza-Friedel–Crafts Reaction

Krishnan, C. G.; Kondo, M.; Yasuda, Y.; Fan, D.; Nakamura, K.; Wakabayashi, Y.; Sasai, H.; Takizawa, S. Chem. Commun. 2023, 59, 9956 (DOI).

6. Photoswitchable Chiral Organocatalysts: Photocontrol of Enantioselective Reactions

Kondo, M.; Nakamura, K.; Krishnan, C.G.; Sasai, H.; Takizawa, S. Chem. Rec. 2023, 23, e202300040 (DOI).

7. Bayesian Optimization-assisted Screening to Identify Improved Reaction Conditions for Spiro-dithiolane Synthesis

Kondo, M.; Wathsala, H. D. P.; Ishikawa, K.; Yamashita, D.; Miyazaki, T.; Ohno, Y.; Sasai, H.; Washio, T.; Takizawa, S. Molecules, 2023, 28, 5180 (DOI).

8. Electrochemical Synthesis of Hetero[7]helicenes Containing Pyrrole and Furan Rings via an Oxidative Heterocoupling and Dehydrative Cyclization Sequence

Salem, M. S. H.; Khalid, Md. I.; Sako, M.; Higashida, K.; Lacroix, C.; Kondo, M.; Takishima, R.; Taniguchi, T.; Miura, M.; Vo-Thanh, G.; Sasai, H.; Takizawa, S. Adv. Synth. Catal. 2023, 365, 373 (DOI).

9. Two-pot synthesis of unsymmetrical hetero[7]helicenes with intriguing optical properties

Salem, M. S. H.; Khalid, Md. I.; Sasai, H.; Takizawa, S. Tetrahedron 2023, 133, 133266 (DOI).

10. Metal-Free Aerobic C–N Bond Formation of Styrene and Arylamines via Photoactivated Electron Donor-Acceptor Complexation

Fan, D.; Sabri, A.; Sasai, H.; Takizawa, S. Molecules 2023, 28, 356 (DOI).

2022

Original Paper

1. Bayesian optimization with constraint on passed charge for multiparameter screening of electrochemical reductive carboxylation in a flow microreactor

Naito, Y.; Kondo, M.; Nakamura, Y.; Shida, N.; Ishikawa, K.; Washio, T.; Takizawa, S.; Atobe, M. Chem. Commun. 2022, 58, 3893 (DOI) (Selected as Inside Front Cover).

2. Metal-free C(aryl)–P bond cleavage: experimental and computational studies of the Michael addition/aryl migration of triarylphosphines to alkenyl esters

Sako, M.; Kanomata, K.; Mohamed, S. H. S.; Furukawa, T.; Sasai H.; Takizawa, S. Org. Chem. Front. 2022, 9, 2187 (DOI).

3. Photoswitchable chiral cation-binding catalyst: Photocontrol of catalytic activity on enantioselective aminal synthesis

Krishnan, C.; Kondo, M.; Nakamura, K.; Sasai, H.; Takizawa, S. Org. Lett. 2022, 24, 2670 (DOI) (Selected as Front Cover).

4. DAST-mediated ring-opening of cyclopropyl silyl ethers in nitriles: Facile synthesis of allylic amides via Ritter-type process

Kirihara, M.; Nakamura, R.; Nakakura, K.; Tujimoto, K.; Mohamed S. H. S.; Suzuki, T.; Takizawa, S. Org. Biomol. Chem. 2022, 20, 6558 (DOI).

5. New anionic cobalt(III) complexes enable enantioselective synthesis of spiro-fused oxazoline and iodoacetal derivatives

Salem, M. S. H. and Takizawa, S. Front. Chem. 2022, 10:1034291 (DOI).

6. Bayesian optimization-driven parallel-screening on multi-parameters of micromixer-type and organocatalytic conditions in the flow biaryl synthesis

Kondo, M.; Wathsala, H. D. P.; Salem, M. S. H.; Ishikawa, H.; Hara, S.; Takaai, T.; Washio, T.; Sasai, H.; Takizawa, S. Commun. Chem. 2022, 5, 148. (DOI)

7. Atroposelective synthesis of C–C axially chiral compounds via mono- and dinuclear vanadium catalysis

Kumar, A.; Sasai, H.; Takizawa, S. Acc. Chem. Res. 2022, 55, 2949 (DOI).

8. Electrochemical synthesis of heterodehydro[7]helicenes

Khalid, Md. I.; Salem, M. S. H.; Sako, M.; Kondo, M.; Sasai, H.; Takizawa, S. Commun. Chem. 2022, 5, 166 (DOI).

9. Electrochemical Synthesis of 1,1’-Binaphthalene-2,2’-diamines via Transition-Metal-Free Oxidative Homocoupling

Fan, D.; Khalid, Md. I.; Kamble, G. T.; Sasai, H.; Takizawa, S. Sustain. Chem. 2022, 3, 551 (DOI) (Highlighted on the Main Page of the  Journal).

Hiro

10. Two-Step Synthesis, Structure, and Optical Features of a Double Hetero[7]helicene

Salem, M. S. H.; Sabri, A.; Khalid, I.; Sasai, H.; Takizawa, S. Molecules 2022, 27, 9068 (DOI).

2021

Original Paper

1. Preparation of Optically Pure Dinuclear Cobalt(III) Complex with Λ–Configuration as a Dianionic Chiral Catalyst

Salem, M. S. H.; Kumar, A.; Sako, M.; Abe, T.; Takizawa, S.; Sasai, H. Heterocycles, 2021, 103, 225 (DOI).

2. Photoswitchable Chiral Phase Transfer Catalyst

Kondo, M.; Nakamura, K.; Krishnan, C.; Takizawa, S.; Abe, T.; Sasai, H. ACS Catalysis, 2021, 11, 1863(DOI).

＜Highlighted in Synfacts 2021, 17, 442. (DOI)＞

3. Practical Stereoselective Synthesis of C3‐Spirooxindole‐ and C2‐Spiropseudoindoxyl‐Pyrrolidines via Organocatalyzed Pictet‐Spengler Reaction/Oxidative Rearrangement Sequence

Kondo, M.; Matsuyama, N.; Aye, T. Z.; Mattan, I.; Sato, T.; Makita, Y.; Ishibashi, M.; Arai, M.; Takizawa, S.; Sasai, H. Adv. Synth. Catal., 2021, 363, 2648(DOI).

4. Chemo- and Enantioselective Hetero-coupling of Hydroxycarbazoles Catalyzed by a Chiral Vanadium(v) complex

Sako, M.; Higashida, K.; Kamble, G. T.; Kaut, K.; Kumar, A.; Hirose, Y.; Zhou, D.; Suzuki, T.; Rueping, M.; Maegawa, T.; Takizawa, S.; Sasai, H. Org. Chem. Front., 2021, 8, 4878 (DOI).

5. Chiral Vanadium(v)-catalyzed Oxidative Coupling of 4-Hydroxycarbazoles

Kamble, G.; Salem, M.; Abe, T.; Park, H.; Sako, M.; Takizawa, S.; Sasai, H. Chem. Lett., 2021, 50, 1755-1757 (DOI).

6. Azopyridine-based Chiral Oxazolines with Rare-earth Metals for Photoswitchable Catalysis

Nakamura, K.; Kondo, M.; Krishnan, C. G.; Takizawa, S.; Sasai, H. Chem. Commun., 2021, 57, 7414 (DOI).

7. Energy-, Time-, and Labor-saving Synthesis of α-Ketiminophosphonates: Machine-learning-assisted Simultaneous Multiparameter Screening for Electrochemical Oxidation

Kondo, M.; Sugizaki, A.; Khalid, Md. I.; Wathsala, H. D. P.; Ishikawa, K.; Hara, S.; Takaai, T.; Washio, T.; Takizawa, S.; Sasai, H. Green Chem., 2021, 23, 5825 (DOI).

8. Application of an Electrochemical Microflow Reactor for Cyanosilylation: Machine Learning-assisted Exploration of Suitable Reaction Conditions for Semi-large-scale Synthesis

Sato, E.; Fujii, M.; Tanaka, H.; Mitsudo, K.; Kondo, M.; Takizawa, S.; Sasai, H.; Washio, T.; Ishikawa, K.; Suga, S. J. Org. Chem., 2021,86, 16035-16044 (DOI).

9. Chemo- and Regioselective Cross-dehydrogenative Coupling Reaction of 3-Hydroxycarbazoles with Arenols Catalyzed by a Mesoporous Silica-supported Oxovanadium

Kasama, K.; Kanomata, K.; Hinami, Y.; Mizuno, K.; Uetake, Y.; Amaya, T.; Sako, M.; Takizawa, S.; Sasai, H.; Akai, S. RSC Adv. 2021, 11, 35342-35350 (DOI).

2020

Original Paper

1. Vanadium(V) Complex-catalyzed One-pot Synthesis of Phenanthridines via a Pictet-Spengler-Dehydrogenative Aromatization Sequence

Sako, M.; Losa, R.; Takiishi, T.; Vo-Thanh, G.; Takizawa, S.; Sasai, H. Catalysts 2020, 10, 860(DOI)

　　　

2. Catalytic and Enantioselective oxa-Piancatelli Reaction using Chiral Vanadium Complex

Schober, L.; Sako, M.; Takizawa, S.; Gröger, H.; Sasai, H. Chem. Commun. 2020, 56, 10151-10154(DOI)

3. Synthesis of Allylamine Derivatives via Intermolecular Aza-Wacker-Type Reaction Promoted by Palladium–SPRIX Catalyst

Sen, A.; Zhu, L.; Takizawa, S.; Takenaka, K.; Sasai, H. Adv. Synth. Catal. 2020, 362, 3558-3563(DOI)

4. Exploration of Flow Reaction Conditions Using Machine-learning for Enantioselective Organocatalyzed Rauhut-Currier and [3+2] Annulation Sequence
Kondo, M.; Wathsala, H. D. P.; Sako, M.; Hanatani, Y.; Ishikawa, K.; Hara, S.; Takaai, T.; Washio, T.; Takizawa, S.; Sasai, H. Chem. Commun. 2020, 56, 1259-1262. (DOI)

＜Highlighted in Synfacts 2020, 16, 366. (DOI)＞
＜本研究成果はプレスリリースされました＞
EurekAlert!（https://eurekalert.org/pub_releases/2020-02/ou-trs021820.php）
AlphaGalileo（https://www.alphagalileo.org/Item-Display/ItemId/189379）

5. Enantioselective One-pot Synthesis of 3-Azabicyclo[3.1.0]hexanes via Allylic Substitution and Oxidative Cyclization
Chaki, B. M.; Takenaka, K.; Zhu, L.; Tsujihara, T.; Takizawa, S.; Sasai, H. Adv. Synth. Catal. 2020, 362(7), 1537-1547. (DOI)
<Selected as a Very Important Publication (VIP)>

＜Highlighted in Synfacts 2020, 16, 781. (DOI)＞

Book & Review

1. “第三級カルボカチオンの立体制御によるエナンチオ収束型触媒的SN1反応”（Review de Debut）
佐古真，有機合成化学協会誌，Vol.78, No.1 (2020)，60-61.📚

2. Organocatalytic Synthesis of Highly Functionalized Heterocycles by Enantioselective aza-Morita–Baylis–Hillman-type Domino Reactions
Takizawa, S. Chem. Pharm. Bull. 2020, 68, 299-315.📚
<2019年度日本薬学会学術振興賞受賞記念総説>

3. Chiral vanadium complex-catalyzed oxidative coupling of arenols

Sako, M.; Takizawa, S.; Sasai, H. Tetrahedron 2020, 76, 131645. (DOI)

2019

Original Paper

1. Asymmetric Cyclizative Dimerization of (ortho-Alkynyl Phenyl) (Methoxymethyl) Sulfides with Palladium(II) Bisoxazoline Catalyst
Peng, C.; Kusakabe, T.; Kikkawa, S.; Mochida, T.; Azumaya, I.; Dhage, Y. D.; Takahashi, K.; Sasai, H.; Kato, K. Chem. Eur. J. 2019, 25(3), 733-737. (DOI)

2. Chiral Dinuclear Vanadium Complex-mediated Oxidative Coupling of Resorcinols
Sako, M.; Aoki, T.; Zumbrägel, N.; Schober, L.; Gröger, H.; Takizawa, S.; Sasai, H. J. Org. Chem. 2019, 84(3), 1580-1587. (DOI)
<Selected as a Cover Picture>

3. Room-Temperature, Metal-Free and One-Pot Preparation of 2H-Indazoles via Mills Reaction and Cyclization Sequence
Kondo, M.; Takizawa, S.; Jiang, Y.; Sasai, H. Chem. Eur. J. 2019, 25(42), 9866-9869. (DOI)

Book & Review

1. キラルバナジウム触媒によるヘリセン様化合物の簡便合成
佐古　真，滝澤　忍，笹井　宏明，生産と技術 2019, 71(2), 77-80.
The Development of Efficient Synthesis for Oxahelicenes Using Chiral Vanadium Catalyst
Sako, M.; Takizawa, S.; Sasai, H. 生産と技術 2019, 71(2), 77-80.

2018

Original Paper

1. Asymmetric Oxidative Coupling of Hydroxycarbazoles: Facile Synthesis of (+)-Bi-2-hydroxy-3-methylcarbazole
Sako, M.; Sugizaki, A.; Takizawa, S. Bioorg. Med. Chem. Lett. 2018, 28, 2751-2753. (DOI)
(Dedicated to Professor Dr. Dale L. Boger on the occasion of his 65th birthday.)

2. Enantioselective Synthesis of Spiro (isoxazole-isoxazoline) Hybrid Ligand
Chaki, B. M.; Wakita, K.; Takizawa, S.; Takenaka, K.; Sasai, H. Heterocycles 2018, 97, 493–505. (DOI)

3. Phosphine-Catalyzed Dual Umpolung Domino Michael Reaction: Facile Synthesis of Hydroindole- and Hydrobenzofuran-2-Carboxylates
Kishi, K.; Takizawa, S.; Sasai, H. ACS Catal. 2018, 8, 5228-5232. (DOI)

4. Vanadium-Catalyzed Dehydrogenation of N‑Heterocycles in Water
Zumbrägel, N.; Sako, M.; Takizawa, S.; Sasai, H.; Gröger, H. Org. Lett. 2018, 20, 4723-4727. (DOI)

5. Enantioselective Aza-Wacker-Type Cyclization Promoted by Pd-SPRIX Catalyst
Sen, A.; Takenaka, K.; Sasai, H. Org. Lett. 2018, 20, 6827-6831. (DOI)

Book & Review

1. “多機能有機分子不斉触媒を用いる環境調和型ドミノ反応の開発”
「有機分子触媒の開発と工業利用」
笹井宏明、滝澤忍，シーエムシー出版 (2018) 220-232.📚

2. “ベンゼンの触媒的非対称化を鍵とするパンクラチスタチン類の不斉全合成”
ファルマシア「トピックス」
佐古真，ファルマシア, 第54巻7号 (2018)，710.📚

3. “キラルバナジウム触媒を用いるエナンチオ選択的酸化カップリング反応の開発と応用”
佐古真、滝澤忍、笹井宏明，有機合成化学協会誌，Vol.76, No.9 (2018)，874-884.📚
“Chiral Vanadium Complex-catalyzed Enantioselective Oxidative Coupling Reactions”
Sako, M.; Takizawa, S.; Sasai, H. J. Synth. Org. Chem. Jpn. 2018, 76, 874–884. (DOI)

2017

Original Paper

1. Facile Synthesis of Spirooxindoles via an Enantioselective Organocatalyzed Sequential Reaction of Oxindoles with Ynone
Takizawa, S.; Kishi, K.; Kusaba, M.; Bai, J.; Suzuki, T.; Sasai, H. Heterocycles 2017, 95(2), 761-767. (DOI)

2. Short Syntheses of 4-Deoxycarbazomycin B, Sorazolon E, and (+)-Sorazolon E2
Sako, M.; Ichinose, K.; Takizawa, S.; Sasai, H. Chem. Asian J. 2017, 12(12), 1305–1308. (DOI)

3. Determination of the Absolute Configuration of Compounds Bearing Chiral Quaternary Carbon Centers Using the Crystalline Sponge Method
Sairenji, S.; Kikuchi, T.; Abozeid, M. A.; Takizawa, S.; Sasai, H.; Ando, Y.; Ohmatsu, K.; Ooi, T.; Fujita, M. Chem. Sci. 2017, 8(7), 5132–5136. (DOI)

4. Enantioselective Synthesis of Tetrahydrocyclopenta[b]indole Bearing a Chiral Quaternary Carbon Center via Pd(II)-SPRIX-Catalyzed C–H Activation
Abozeid, M. A.; Sairenji, S.; Takizawa, S.; Fujita, M.; Sasai, H. Chem. Commun. 2017, 53, 6887-6890. (DOI)

5. Multifunctional Catalysis: Stereoselective Construction of α-Methylidene-γ-Lactams via Amidation/Rauhut–Currier Sequence
Kishi, K.; Arteaga, F. A.; Takizawa, S.; Sasai, H. Chem. Commun. 2017, 53. 7724-7727. (DOI)
<Selected as an Inside Front Cover>

6. Reversal of Enantioselectivity Approach to BINOLs via Single and Dual 2‑Naphthol Activation Modes
Kim, H. Y.; Takizawa, S.; Sasai, H.; Oh, K. Org. Lett. 2017, 19(14), 3867-3870. (DOI)

7. Enantio- and Diastereoselective Betti/aza-Michael Sequence: Single Operated Preparation of Chiral 1,3-Disubstituted Isoindolines
Takizawa, S.; Sako, M.; Abozeid, M. A.; Kishi, K.; Wathsala, H. D. P.; Hirata, S.; Murai, K.; Fujioka, H.; Sasai, H. Org. Lett. 2017, 19(19), 5426-5429. (DOI)

8. Chiral Organocatalyzed Intermolecular Rauhut–Currier Reaction of Nitroalkenes with Ethyl Allenoate
Takizawa, S.; Sako, M.; Kishi, K.; Shigenobu, M.; Vo-Thanh, G.; Sasai, H. Chem. Pharm. Bull. 2017, 65, 997-999. (DOI)
<Selected as a Cover Picture>

Book & Review

1. 多機能有機分子触媒を用いるエナンチオ選択的ドミノ反応の開発
滝澤忍、笹井宏明，化学工業，第68巻9号 (2017), 31-38.

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2016

Original Paper

1. Enantioselective Organocatalytic Oxidation of Ketimines
Takizawa, S.; Kishi, K.; Abozeid, M. A.; Murai, K.; Fujioka, H.; Sasai, H. Org. Biomol. Chem. 2016, 14, 761-767. (DOI)

2. Asymmetric Brønsted Acid Catalyzed Substitution of Diaryl Methanols with Thiols and Alcohols for the Synthesis of Chiral Thioethers and Esters
Chatupheeraphat, A.; Liao, H.-H.; Mader, S.; Sako, M.; Sasai, H.; Atodiresei, I.; Rueping, M. Angew. Chem. Int. Ed. 2016, 55, 4803-4807. (DOI)

3. Efficient Enantioselective Synthesis of Oxahelicenes Using Redox/Acid Cooperative Catalysts
Sako, M.; Takeuchi, Y.; Tsujihara, T.; Kodera, J.; Kawano, T.; Takizawa, S.; Sasai, H. J. Am. Chem. Soc. 2016, 138(36), 11481-11484. (DOI)

4. Organocatalyzed [4+2] Annulation of All-Carbon Tetrasubstitued Alkenes with Allenoate: Synthesis of Highly Functionalized 2H, and 4H-Pyran Derivatives
Ngo, T.-Thuy-Duong ; Kishi, K.; Sako, M.; Shigenobu, M.; Bournaud, C.; Toffano, M.; Guillot, R.; Baltaze, J.-P.; Takizawa, S.; Sasai, H.; Vo-Thanh, G. ChemistrySelect 2016, 1(17), 5414-5420. (DOI)

Book & Review

1. “有機分子触媒を用いる脱古典的ドミノ反応の開発動向”
「有機分子触媒の化学　モノづくりのパラダイムシフト」（日本化学会　編）
滝澤忍，化学同人 (2016) 206-207.

2. A Career in Catalysis: Masakatsu Shibasaki
Kumagai. N.; Kanai, M.; Sasai, H. ACS catal. 2016, 6(7), 4699-4709. (DOI)

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2015

Original Paper

1. Enantioselective Construction of C₂-Symmetric Spiro Skeleton through Intramolecular Copper-Catalyzed N-Arylation
Takenaka, K.; Sako, M.; Takatani, S.; Sasai, H. ARKIVOC 2015, ii, 52-63. (DOI)

2. Pd-Catalyzed Enantioselective Intramolecularα-Arylation ofα-Substituted Cyclic Ketones: Facile Synthesis of Functionalized Chiral Spirobicycles
Fan, L.; Takizawa, S.; Takeuchi, Y.; Takenaka, K.; Sasai, H. Org. Biomol. Chem. 2015, 13, 4837-4840. (DOI)

3. Palladium(II)-Catalyzed Intramolecular Carboxypalladation–Olefin Insertion Cascade: Direct Access to Indeno[1,2,-b]furan-2-ones
Vinoth, P.; Vivekanand, T.; Suryavanshi, P. A.; Menendez, J. C.; Sasai, H.; Sridharan, V. Org. Biomol. Chem. 2015, 13, 5175-5181. (DOI)

4. Structural Features and Asymmetric Environment of i-Pr-SPRIX Ligand
Takenaka, K.; Lin, X.; Takizawa, S.; Sasai, H. Chirality, 2015, 27, 532-537.. (DOI)

5. Enantioselective and Aerobic Oxidative Coupling of 2-Naphthol Derivatives Using Chiral Dinuclear Vanadium(V) Complex in Water
Sako, M.; Takizawa, S.; Yoshida, Y.; Sasai, H. Tetrahedron: Asymmetry 2015, 26, 613-616. (DOI)

6. Pd(II)-Catalyzed Diastereoselective and Enantioselective Domino Cyclization/Cycloaddition Reactions of Alkenyl Oximes for Polycyclic Heterocycles with Four Chiral Stereogenic Centers
Abozeid, M. A.; Takizawa, S.; Sasai, H. Tetrahedron Lett. 2015, 56, 4316-4319. (DOI)

7. Palladium-Catalyzed Direct C–H Arylation of Isoxazoles at the 5-Position
Shigenobu, M.; Takenaka, K.; Sasai, H. Angew. Chem. Int. Ed. 2015, 54, 9572-9576. (DOI)

8. An Enantioselective Organocatalyzed aza-Morita-Baylis-Hillman Reaction of Isatin-derived Ketimines with Acrolein
Yoshida, Y.; Sako, M.; Kishi, K.; Sasai, H.; Hatakeyama, S.; Takizawa, S. Org. Biomol. Chem. 2015, 13, 9022-9028. (DOI)

9. One-Pot Catalysis Using a Chiral Iridium Complex/Bronsted Base: Catalytic Asymmetric Synthesis of Cataponol
Suzuki, T.; Ismiyarto; Ishizaka, Y.; Zhou, D.-Y.; Asano, K.; Sasai, H. Org. Lett. 2015, 17, 5176-5179. (DOI)

10. Phosphine-Catalyzed β,γ-Umpolung Domino Reaction of Allenic Esters: Facile Synthesis of Tetrahydrobenzofuranones Bearing a Chiral Tetrasubstituted Carbon Stereogenic Center
Takizawa, S.; Kishi, K.; Yoshida, Y.; Mader, S.; Arteaga, F. A.; Lee, S.; Hoshino, M.; Rueping, M.; Fujita, M.; Sasai, H. Angew. Chem. Int. Ed. 2015, 54, 15511-15515. (DOI)
<Highlighted in Synfacts 2016, 12, 129>

Book & Review

1. Vanadium in Asymmetric Synthesis: Emerging Concepts in Catalyst Design and Applications
Takizawa, S.; Gröger, H.; Sasai, H. Chem. Eur. J. 2015, 21, 8992-8997. (DOI)

2. パラジウム2価／4価触媒サイクルを経るアルケン・アルキンの1,2−二官能基化反応
竹中和浩, 有機合成化学協会誌, 第73巻10号 (2015), 964-976.

3. Sasai, H.; Takizawa, S. “Vanadium and Niobium-catalyzed Enantioselective Reactions” In Sustainable Catalysis: With Non-endangered Metals, Part 1, North, M. Ed, Royal Society of Chemistry; UK, 2015; pp 216-249.

4. パラジウム(II)錯体の反応性制御　新規エナンチオ選択的パラジウム触媒反応の開発
竹中和浩, 化学と工業, 第68巻12号 (2015), 1123-1124.

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2014

Original Paper

1. Enantioselective Oxidative-Coupling of Polycyclic Phenols
Takizawa, S.; Kodera, J.; Yoshida, Y.; Sako, M.; Breukers, S.; Enders, D.; Sasai, H. Tetrahedron 2014, 70, 1786-1793. (DOI)

2. Enantioselective Organocatalyzed Formal [4+2] Cycloaddition of Ketimines with Allenoates: Easy Access to a Tetrahydropyridine Framework with a Chiral Tetrasubstituted Stereogenic Carbon Center
Takizawa, S.; Arteaga, F. A.; Yoshida, Y.; Suzuki, M.; Sasai, H. Asian J. Org. Chem. 2014, 3, 412-415. (DOI)

3. Palladium Enolate Umpolung: Cyclative Diacetoxylation of Alkynyl Cyclohexadienones Promoted by a Pd/SPRIX Catalyst
Takenaka, K.; Mohanta, S. C.; Sasai, H. Angew. Chem. Int. Ed. 2014, 53, 4675-4679. (DOI)
<Highlighted in Synfacts 2014, 10, 619>

4. C₃-Symmetric Chiral Trisimidazoline-catalyzed Friedel–Crafts (FC)-type Reaction
Takizawa, S.; Hirata, S.; Murai, K.; Fujioka, H.; Sasai, H. Org. Biomol. Chem. 2014, 12, 5827-5830. (DOI)

5. Facile Regio- and Stereoselective Metal-Free Synthesis of All-Carbon Tetrasubstituted Alkenes Bearing a C(sp³)−F Unit via Dehydroxyfluorination of Morita−Baylis−Hillman (MBH) Adducts
Takizawa, S.; Arteaga, F. A.; Kishi, K.; Hirata, S.; Sasai, H. Org. Lett. 2014, 16, 4162-4165. (DOI)

Book & Review

1. Takizawa, S.; Sasai, H. “Metal-catalyzed Enantio- and Diastereoselective C–C Bond-forming Reactions in Domino Processes” In Domino Reactions: Concepts for Efficient Organic Synthesis, Tietze, L. F. Ed, Wiley-VCH Verlag GmbH & Co. KGaA; Chapter 11, pp. 419-462 (2014).

2. Takizawa, S.; Sasai, H. "Enantioselective Acid-Base Organocatalyzed Domino Reactions Based on aza-Morita-Baylis-Hillman Process", J. Synth. Org. Chem. Jpn., vol. 72, No. 7, pp. 781-796 (2014).

3. Sasai, H. “The Henry (Nitroaldol) Reaction” In Comprehensive Organic Syntheses, Second Edition, Knochel, P.; Molander, G. A. Eds, Elsevier; Amsterdam; Volume 2, Chapter 2-13, pp 543-570 (2014).

4. Takenaka, K; Sasai, H. “Addition Reactions with Formation of Carbon–Oxygen Bonds: (iv) The Wacker Oxidation and Related Reactions” In Comprehensive Organic Syntheses, Second Edition, Knochel, P.; Molander, G. A. Eds, Elsevier; Amsterdam; Volume 7, Chapter 7-17, pp 431-491 (2014).

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2013

Original Paper

1. Facile Synthesis of α-Methylidene-γ-Butyrolactones: Intramolecular Rauhut-Currier Reaction Promoted by Chiral Acid-Base Organocatalysts
Takizawa, S.; Nguyen, T. M.-N.; Grossmann, A.; Suzuki, M.; Enders, D.; Sasai H. Tetrahedron 2013, 69, 1202-1209. (DOI)

2. Vanadium-Catalyzed Enantioselective Friedel-Crafts-Type Reactions
Takizawa, S.; Arteaga, F. A.; Yoshida, Y.; Kodera, J.; Nagata, Y.; Sasai, H. Dalton Trans. 2013, 42, 11787-11790. (DOI)

3. DFT Study on 5-Endo-Trig-Type Cyclization of 3-Alkenoic Acids Using Pd–SPRIX Catalyst: Importance of the Rigid Spiro Framework for Both Selectivity and Reactivity
Gabr, R. K. M.; Hatakeyama, T.; Takenaka, K.; Takizawa, S.; Okada, Y.; Nakamura, M.; Sasai, H. Chem. Eur. J. 2013, 19, 9518-9525. (DOI)

4. o-(Hydroxyalkyl) P-Chirogenic Phosphines as Functional Chiral Lewis Bases
Rémond, E.; Bayardon, J.; Takizawa, S.; Rousselin, Y.; Sasai, H.; Jugé, S. Org. Lett. 2013, 15, 1870-1873. (DOI)

5. Carbonylation of Propargyl Carbamates with Palladium(II) Bisoxazoline Catalysts: Efficient Synthesis of 5-Methyl-3(2H)-furanones
Kusakabe, T.; Takahashi, T.; Shen, R.; Ikeda, A.; Dhage, Y. D.; Kanno, Y.; Inouye, Y.; Sasai, H.; Mochida, T.; Kato, K. Angew. Chem. Int. Ed. 2013, 52, 7845-7849. (DOI)

6. Enantioselective Multicatalytic Synthesis of α-Benzyl-β-hydroxyindan-1-ones
Suzuki, T.; Ishizaka, Y.; Ghozati, K.; Zhou, D.-Y.; Asano, K.; Sasai, H. Synthesis 2013, 45, 2134-2136. (DOI)

7. Pd(II)-SDP-Catalyzed Enantioselective 5-Exo-Dig Cyclization of γ-Alkynoic Acids: Application to the Synthesis of Functionalized Dihydrofuran-2(3H)-ones Containing a Chiral Quaternary Carbon Center
Sridharan, V.; Fan, L.; Takizawa, S.; Suzuki, T.; Sasai, H. Org. Biomol. Chem. 2013, 11, 5936-5943. (DOI)

8. P-Chirogenic Organocatalysts: Application to the aza-Morita-Baylis-Hillman (aza-MBH) Reaction of Ketimines
Takizawa, S.; Rémond, E.; Arteaga, F. A.; Yoshida, Y.; Sridharan, V.; Bayardon, J.; Jugé S.; Sasai, H. Chem. Commun. 2013, 49, 8392-8394. (DOI)
<Highlighted in Synfacts 2013, 9, 1297>

9. Organocatalyzed Formal [2+2] Cycloaddition of Ketimines with Allenoates: Facile Access to Azetidines with a Chiral Tetrasubstituted Carbon Stereogenic Center
Takizawa, S.; Arteaga, F. A.; Yoshida, Y.; Suzuki, M.; Sasai, H. Org. Lett. 2013, 15, 4142-4145. (DOI)

10. Chiral Bifunctional Organocatalysts Bearing a 1,3-Propanediamine Unit for the aza-MBH Reaction
Hirata, S.; Tanaka, K.; Matsui, K.; Arteaga, F. A.; Yoshida, Y.; Takizawa, S.; Sasai, H. Tetrahedron: Asymmetry 2013, 24, 1189-1192. (DOI)

11. Enantioselective Pd(II)/Pd(IV) Catalysis Utilizing SPRIX Ligand: Efficient Construction of Chiral 3-Oxy-Tetrahydrofurans
Takenaka, K.; Dhage, Y. D.; Sasai, H. Chem. Commun. 2013, 49, 11224-11226. (DOI)
<Highlighted in Synfacts 2014, 10, 275>

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2012

Original Paper

1. Enantioselective Synthesis of a-Alkylidene-g-Butyrolactones: Intramolecular Rauhut-Currier Reaction Promoted by Acid/Base Organocatalysts
Takizawa, S.; Nguyen, T. M.-N.; Grossmann, A.; Enders, D.; Sasai H. Angew. Chem., Int. Ed. 2012, 51, 5423-5426. (DOI)
<Highlighted in Synfacts 2012, 8, 787>

2. Design and Synthesis of Spiro Bis(1,2,3-triazolium) Salts As Chiral Ionic Liquids
Yoshida, Y.; Takizawa, S.; Sasai, H. Tetrahedron: Asymmetry 2012, 23, 843-851. (DOI)

Book & Review

1. Sasai, H. “Direct C-C Bond Formation (Henry, Aza-Henry)” in Comprehensive Chirality, Carreira, E. M. and Yamamoto, H. Ed., Elsevier B. V.; Amsterdam, 4, pp. 214-242 (2012).

2. Sasai, H. and Takizawa, S. “C-C Bond Formation: (aza) Morita-Baylis-Hillman Reaction” in Comprehensive Chirality, Carreira, E. M. and Yamamoto, H. Ed., Elsevier B. V.; Amsterdam, 6, pp. 234-263 (2012).

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2011

Original Paper

1. An Enantioselective Organocatalyzed aza-MBH Domino Process: Application to the Facile Synthesis of Tetrahydropyridines
Takizawa, S.; Inoue, N.; Sasai H. Tetrahedron Lett. 2011, 52, 377-380. (DOI)

2. Pd(II)-SPRIX Catalyzed Enantioselective Construction of Pyrrolizines/Pyrroloindoles Employing Molecular Oxygen As the Sole Oxidant
Ramalingan, C.; Takenaka, K.; Sasai, H. Tetrahedron 2011, 67, 2889-2894. (DOI).

3. Chlorinative Cyclization of 1,6-Enynes by Enantioselective Palladium(II)/Palladium(IV) Catalysis
Takenaka, K.; Hashimoto, S.; Takizawa, S.; Sasai, H. Adv. Synth. Catal. 2011, 353, 1067-1070. (DOI).

4. Enantioselective Cyclization of 4-Alkenoic Acids via an Oxidative Allylic C-H Esterification
Takenaka, K.; Akita, M.; Tanigaki, Y.; Takizawa, S.; Sasai, H. Org. Lett. 2011, 13, 3506-3509. (DOI).
<Highlighted in Synfacts 2011, 991>

5. A Bifunctional Spiro-Type Organocatalyst with High Enantiocontrol: Application to the Aza-Morita-Baylis-Hillman Reactions
Takizawa, S.; Kiriyama, K.; Ieki, K.; Sasai, H. Chem. Commun. 2011, 47, 9227-9229. (DOI).

6. Synthesis of Spiro Bis(1,2,3-triazolium) Salts As Chiral Ionic Liquids
Yoshida, Y.; Takizawa, S.; Sasai, H. Tetrahedron Lett. 2011, 52, 6877-6879. (DOI).

Book & Review

1. Immobilization of Multicomponent Asymmetric Catalysts (MACs)
「Polymeric Chiral Catalyst Design and Chiral Polymer Synthesis」（Itsuno, S. Ed.）
Takizawa, S.; Sasai, H. John Wiley & Sons, (2011) 293-322.

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2010

Original Paper

1. Asymmetric Synthesis of Chiral Spiro Bis(isoxazoline) and Spiro (Isoxazole-Isoxazoline) Ligands
Takenaka, K.; Nagano, T.; Takizawa, S.; Sasai, H. Tetrahedron: Asymmetry 2010, 21, 379-381. (DOI)

2. Enantioselective 6-Endo-Trig Wacker-Type Cyclization of 2-Geranylphenols: Application to Facile Synthesis of (−)-Cordiachromene
Takenaka, K.; Tanigaki, Y.; Patil, M. L.; Rao, C. V. L.; Takizawa, S.; Suzuki, T.; Sasai, H. Tetrahedron: Asymmetry 2010, 21, 767-770. (DOI)

3. Acid-Base Organocatalysts for the Aza-Morita-Baylis-Hillman Reaction of Nitroalkenes
Takizawa, S.; Horii, A.; Sasai, H. Tetrahedron: Asymmetry 2010, 21, 891-894. (DOI)

4. Enantioselective Wacker-Type Cyclization of 2-Alkenyl-1,3-Diketones Promoted by Pd-SPRIX Catalyst
Takenaka, K.; Mohanta, S. C.; Patil, M. L.; Rao, C. V. L.; Takizawa, S.; Suzuki, T.; Sasai, H. Org. Lett. 2010, 12, 3480-3483. (DOI)
<Highlighted in Synfacts 2010, 1263>

5. Formal Total Synthesis of Ottelione Using Iridium-Catalyzed Oxidative Desymmetrization
Suzuki, T.; Ghozati, K.; Zhou, D.-Y.; Katoh, T.; Sasai, H. Tetrahedron 2010, 66, 7562-7568. (DOI)

6. Enantioselective Synthesis of Isoindolines: Organocatalyzed Domino Process Based on the aza-Morita-Baylis-Hillman (aza-MBH) Reaction
Takizawa, S.; Inoue, N.; Hirata, S.; Sasai H. Angew. Chem. Int. Ed. 2010, 49, 9725-9729. (DOI)
<Highlighted in Synfactcs 2011, 221>

7. Pd-Catalyzed 5-Endo-Trig-Type Cyclization of b,g-Unsaturated Carbonyl Compounds: an Efficient Ring Closing Reaction to Give g-Butenolides and 3-Pyrrolin-2-ones
Bajracharya, G. B.; Koranne, P. S.; Nadaf, R. N.; Gabr, R. K. M.; Takenaka, K.; Takizawa, S.; Sasai H. Chem. Commun. 2010, 46, 9064-9066. (DOI)

Book & Review

1. 「使える！有機合成反応241実践ガイド」（丸岡啓二, 野崎京子, 石井康敬, 大寺純蔵, 富岡清　編著）
笹井宏明, 滝澤忍, 竹中和浩, 化学同人 (2010) 224-225, 262-263, 280-281, 360-361.

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2009

Original Paper

1. Dicationic Palladium(II)-Spiro bis(isoxazoline) Complex for Highly Enantioselective Isotactic Copolymerization of CO with Styrene Derivatives
Bajracharya, G. B.; Koranne, P. S.; Tsujihara, T.; Takizawa, S.; Onitsuka, K.; Sasai, H. Synlett 2009, 310-314. (DOI)

2. Pd^II/Pd^IV Catalytic Enantioselective Synthesis of Bicyclo[3.1.0]hexanes via Oxidative Cyclization of Enynes
Tsujihara, T.; Takenaka, K.; Onitsuka, K.; Hatanaka, M.; Sasai, H. J. Am. Chem. Soc. 2009, 131, 3452-3453. (DOI)
<Highlighted in Synfacts 2009, 635>

3. Enantioselective Synthesis of C₂-Symmetric Spirobilactams via Pd-Catalyzed Intramolecular Double N-Arylation
Takenaka, K.; Itoh, N.; Sasai, H. Org. Lett. 2009, 11, 1483-1486. (DOI)
<Highlighted in Synfacts 2009, 602>

4. Development of Chiral Spiro Ligands for Metal-Catalyzed Asymmetric Reactions
Bajracharya, G. B.; Arai, M. A.; Koranne, P. S.; Suzuki, T.; Takizawa, S.; Sasai, H. Bull. Chem. Soc. Jpn. 2009, 82, 285-302. (DOI)

5. One-pot Preparation of Chiral Dinuclear Vanadium(V) Complex
Takizawa, S.; Rajesh, D.; Katayama, T.; Sasai, H. Synlett 2009, 1667-1669. (DOI)

6. Regio- and Enantioselective Allylation of Indole Catalyzed by a Planar-chiral Cyclopentadienyl-Ruthenium Complex
Onitsuka, K.; Kameyama, C.; Sasai, H. Chem. Lett. 2009, 38, 444-445. (DOI)

7. Ir-Catalyzed Oxidative Desymmetrization of meso-Diols
Suzuki, T.; Ghozati, K.; Katoh, T.; Sasai, H. Org. Lett. 2009, 11, 4286-4288. (DOI)
<Highlighted in Synfacts 2010, 76>

8. Enantioselective Intramolecular Oxidative Aminocarbonylation of Alkenylureas Catalyzed by Palladium-Spiro Bis(isoxazoline) Complexes
Tsujihara, T.; Shinohara, T.; Takenaka, K.; Takizawa, S.; Onitsuka, K.; Hatanaka, M.; Sasai, H. J. Org. Chem. 2009, 74, 9274-9279. (DOI)

Book & Review

1. “第10章　酸塩基複合型触媒　アザMBH反応を中心として”
「化学フロンティア21　進化を続ける有機触媒−有機合成を革新する第三の触媒」　（丸岡啓二　編）
笹井宏明, 滝澤忍, 化学同人 (2009) 120-127.

2. 複数の構成要素を持つ不斉触媒“Multicomponent Asymmetric Catalyst (MAC)”の固定化
滝澤忍, 荒井孝義, 笹井宏明, 有機合成化学協会誌, 第67巻3号 (2009), 194-207.

3. Development of Dinuclear Vanadium Catalysts for Enantioselective Coupling of 2-Naphthols via a Dual Activation Mechanism
Takizawa, S. Chem. Pharm. Bull. 2009, 57, 1179-1188.

4. 二重活性化能を有する酸塩基型不斉有機分子触媒の開発とaza-Morita-Baylis-Hillman反応への展開
滝澤忍, 薬学雑誌, 第129巻10号 (2009), 1201-1210.

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2008

Original Paper

1. Regio- and Enantioselective O-Allylation of Phenol and Alcohol Catalyzed by a Planar-Chiral Cyclopentadienyl Ruthenium Complex
Onitsuka, K.; Okuda, H.; Sasai, H. Angew. Chem. Int. Ed. 2008, 47, 1454-1457. (DOI)
<Highlighted in Synfacts 2008, 380>

2. Dual Activation in Oxidative Coupling of 2-Naphthols Catalyzed by Chiral Dinuclear Vanadium Complexes
Takizawa, S.; Katayama, T.; Somei, H.; Asano, Y.; Yoshida, T.; Kameyama, C.; Rajesh, D.; Onitsuka, K.; Suzuki, T.; Mikami, M.; Yamataka, H.; Jayaprakash, D.; Sasai, H. Tetrahedron 2008, 64, 3361-3371. (DOI)

3. Chiral Dinuclear Vanadium(V) Catalysts for Oxidative Coupling of 2-Naphthols
Takizawa, S.; Katayama, T.; Kameyama, C.; Onitsuka, K.; Suzuki, T.; Yanagida, T.; Kawai, T.; Sasai, H. Chem. Commun. 2008, 1810-1812. (DOI)
<Highlighted in Synfacts 2008, 737>

4. Divergent Synthesis of Chiral Spiro (Isoxazole-Isoxazoline) Hybrid Ligands
Takenaka, K.; Nakatsuka, S.; Tsujihara, T.; Koranne, P. S.; Sasai, H. Tetrahedron: Asymmetry 2008, 19, 2492-2496. (DOI)

5. Recent Development on Chiral Ionic Liquids: Design, Synthesis, and Applications
Patil, M. L.; Sasai, H. Chem. Rec. 2008, 8, 98-108. (DOI)

6. Dinuclear Chiral Vanadium Catalysts for Oxidative Coupling of 2-Naphthols via a Dual Activation Mechanism
Takizawa, S.; Katayama, T.; Sasai, H. Chem. Commun. 2008, 4113-4122. (DOI)

Book & Review

1. 「Asymmetric Phase Transfer Catalysis」（Maruoka, K. Eds.）
Sasai, H.; Patil, M. L. Wiley-VCH, (2008) 135-159.

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2007

Original Paper

1. Synthesis of Novel Spiro Imidazolium Salts as Chiral Ionic Liquids
Patil, M. L.; Rao, C. V. L.; Takizawa, S.; Takenaka, K.; Onitsuka, K.; Sasai, H. Tetrahedron 2007, 63, 12702-12711. (DOI)

2. Development of New Methods towards Efficient Immobilization of Enantioselective Catalysts
Takizawa, S.; Patil, M. L.; Marubayashi, K.; Sasai, H. Tetrahedron 2007, 63, 6512-6528. (DOI)

3. Design and Synthesis of Chiral Hybrid Spiro (isoxazole-isoxazoline) Ligands
Koranne, P. S.; Tsujihara, T.; Arai, M. A.; Bajracharya, G. B.; Suzuki, T.; Onitsuka, K.; Sasai, H. Tetrahedron: Asymmetry 2007, 18, 919-923. (DOI)

4. Enantioselective Glyoxylate-ene Reaction using a Novel Spiro Bis(isoxazoline) Ligand in Copper Catalysis
Wakita, K.; Bajracharya, G. B.; Arai, M. A.; Takizawa, S.; Suzuki, T.; Sasai, H. Tetrahedron: Asymmetry 2007, 18, 372-376. (DOI)

5. Optical Resolution of Tetra Isopropyl-substituted Spiro Bis(isoxazoline) i-Pr-SPRIX
Takizawa, S.; Yogo, J.; Tsujihara, T.; Onitsuka, K.; Sasai, H. J. Organomet. Chem. 2007, 692, 495-498. (DOI)

6. Novel Azalides Derived from Sixteen-membered Macrolides. I. Isolation of the Mobile Dialdehyde and its One-pot Macrocyclization with an Amine
Miura, T.; Natsume, S.; Kanemoto, K.; Atsumi, K.; Fushimi, H.; Sasai, H.; Arai, T.; Yoshida, T.; Ajito. K. J. Antibiot. 2007, 60, 407-435.

7. フッ素アパタイトを利用した環境に優しい無溶媒触媒反応
市原潤子, 材料の科学と工学 2007, 44, 157-162.

8. Bifunctional Organocatalysts for Enantioselective Aza-Morita-Baylis-Hillman (Aza-MBH) Reactions
Takizawa, S.; Matsui, K.; Sasai, H. J. Synth. Org. Chem. Jpn. 2007, 65 (11), 1089-1098.

9. 酸−塩基型不斉有機分子触媒を用いるaza-Morita-Baylis-Hillman反応
笹井宏明, 滝澤忍, 松井嘉津也, THE CHEMICAL TIMES KANTO CHEMICAL CO. INC. 2007, 1, 3-8.

Patent

1. 「固相系酸化反応システム」
市原潤子, 山口俊郎, 特願2007-022073

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2006

Original Paper

1. Design and Synthesis of Novel Chiral Spiro Ionic Liquids
Patil, M. L.; Rao, C. V. L.; Yonezawa, K.; Takizawa, S.; Onitsuka, K.; Sasai, H. Org. Lett. 2006, 8, 227-230. (DOI)

2. Conformational Lock in Brfnsted Acid - Lewis Base Organocatalyst for the aza-Morita-Baylis-Hillman Reaction
Matsui, K.; Tanaka, K.; Horii, A.; Takizawa, S.; Sasai, H. Tetrahedron: Asymmetry 2006, 17, 578-583. (DOI)

3. A Brfnsted Acid - Lewis Base Organocatalyst for the aza-Morita-Baylis-Hillman Reaction
Matsui, K.; Takizawa, S.; Sasai, H. Synlett 2006, 761-765. (DOI)

4. Development of Efficient Methods for the Immobilisation of Multicomponent Asymmetric Catalysts
Jayaprakash, D.; Takizawa, S.; Arai, T.; Sasai, H. J. Experimental Nanoscience 2006, 1, 477-510. (DOI)

5. Vanadomolybdophosphoric Acid/Fluorapatite Solid-phase System for Aerobic Oxidative Dehydrogenation
Iteya, K.; Ichihara, J.; Sasaki, Y.; Ito, S. Catal. Today 2006, 111, 349-353.

6. Participation of New Active Species in Epoxidation with Cetylpyridinium Dodecatungstate/FAp/Urea-H₂O₂ System
Ichihara, J.; Sasaki, Y. Catal. Today 2006, 117, 120-125.

Book & Review

1. “第18章　酸−塩基型不斉有機分子触媒によるaza-Morita-Baylis-Hillman反応”
「有機分子触媒の新展開」（柴崎正勝　監修）
笹井宏明, 滝澤忍, 松井嘉津也, シ−・エム・シー出版 (2006) 231-242.

Patent

1. 「光学活性スピロビスイソオキサゾリン誘導体とその製造方法およびその金属錯体を用いた不斉触媒反応」
笹井宏明, 脇田和彦, 加藤孝浩, 荒井緑, 特開2006-76939

2. 「光学活性スピロビスイソオキサゾール誘導体およびその製造法、並びにその金属錯体を用いた不斉触媒反応」
笹井宏明, 脇田和彦, 加藤孝浩, 荒井緑, 特開2006-76915

3. 「スピロキラリティを有する第４級アンモニウム塩およびその製造法、並びに該アンモニウム塩を用いた不斉触媒反応」
下元愛, 米澤浩司, 滝澤忍, 笹井宏明, 特開2006-76911

4. 「新規スピロ構造化合物とその製造法」
マヘッシュ　エル　パティル, シラムコッティ　ベンカット　ラクシュマン　ラオ, 滝澤忍, 笹井宏明, 特開2006-76887

5. 「スピロ骨格を持つキラルな相間移動触媒およびその製造法、並びにそれを用いた不斉触媒反応」
米澤浩司, 下元愛, 滝澤忍, 笹井宏明, 特開2006-70001

6. 「Novel organic molecular catalyst having binaphthol skeleton and processes for producing the same and application thereof」
Sasai Hiroaki, Takizawa Shinobu, Matsui Katsuya, Patent No. US 2006-009646

7. 「ビナフトール骨格を有する新規有機分子触媒およびその製造法と応用」
笹井宏明, 滝澤忍, 松井嘉津也, 特開2006-28021

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2005

Original Paper

1. Spiro Crown Ethers Bearing (S )-1,1'-Spirobiindanes as Chiral Backbones
Yonezawa, K.; Patil, M. L.; Sasai, H.; Takizawa, S. Heterocycles 2005, 66, 639-644.

2. Bifunctional Organocatalysts for Enantioselective aza-Morita-Baylis-Hillman Reaction
Matsui, K.; Takizawa, S.; Sasai, H. J. Am. Chem. Soc. 2005, 127, 3680-3681. (DOI)

3. Micelle-Derived Polymer Supports for Enantioselective Catalysts
Takizawa, S.; Patil, M. L.; Yonezawa, F.; Marubayashi, K.; Tanaka, H.; Kawai, T.; Sasai, H. Tetrahedron Lett. 2005, 46, 1193-1197. (DOI)

4. Enantioselective Morita-Baylis-Hillman (MBH) Reaction Promoted by a Heterobimetallic Complex with a Lewis Base
Matsui, K.; Takizawa, S.; Sasai, H. Tetrahedron Lett. 2005, 46, 1943-1946. (DOI)

5. Effective Forms of Hydroxyapatite Disperse Phase in Solvent-Free Epoxidation System
Iteya, K.; Sasaki, Y.; Itoh, S.; Ichihara, J. Phosphorus Res. Bull. 2005, 19, 142-146.

Patent

1. 「不斉合成用触媒の製造方法」
柴崎正勝, 笹井宏明, 田原義博, 特開2005-028363

2. 「エポキシ化合物の製造方法」
市原潤子, 佐々木　洋, 山口俊郎, 野須　勉, 特開2005-104902

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2004

Original Paper

1. Dual Activation in a Homolytic Coupling Reaction Promoted by an Enantioselective Dinuclear Vanadium(IV) Catalyst
Somei, H.; Asano, Y.; Yoshida, T.; Takizawa, S.; Yamataka, H.; Sasai, H. Tetrahedron Lett. 2004, 45, 1841-1844. (DOI)

2. Development of Novel Chiral Spiro Ligand Bearing Oxazolines
Kato, T.; Marubayashi, K.; Takizawa, S.; Sasai, H. Tetrahedron: Asymmetry 2004, 15, 3693-3697. (DOI)

3. Enantioselective Aldol-type Reaction Using Diketene
Kawase, T.; Takizawa, S.; Jayaprakash, D.; Sasai, H. Synth. Commun. 2004, 34, 4487-4492. (DOI)

4. Spiro Bis(isoxazole) as a New Chiral Ligand
Wakita, K.; Arai, M. A.; Kato, T.; Shinohara, T.; Sasai, H. Heterocycles 2004, 62, 831-838.

5. Tetrabutylammonium Phosphomolybdate on Fluorapatite: an Efficient Solid Catalyst for Solvent-free Selective Oxidation of Sulfides
Sasaki, Y.; Ushimaru, K.; Iteya, K.; Nakayama, H.; Yamaguchi, S.; Ichihara, J. Tetrahedron Lett. 2004, 45, 9513-9515. (DOI)

6. Formation of Fluoridated Hydroxyapatite by Competitive Attack of OH- and F- Ions onto a- or b-tricalcium bis(orthophosphate)
Sakamoto, K.; Yamaguchi, S.; Ichihara, J.; Okazaki, M.; Tsunawaki, Y.; Elliott, J. C. J. Ceram. Soc. Jpn. 2004, 112, 6-12. (DOI)

7. The Use of Apatite as Green Disperse-phase for Solvent-free Epoxidation
Sasaki, Y.; Ichihara, J.; Sakamoto, K.; Yamaguchi, S. Phosphorus Research Bull. 2004, 17, 215-218.

8. Solvent-free Catalytic Oxidation System Using Apatite Disperse Phase
Ichihara, J.; Iteya, K.; Kambara, A.; Yamaguchi, S.; Sasaki, Y. Catalysts & Catalysis 2004, 46, 57-59.

9. Asymmetric ligands bearing spiro skeleton and their applications to enantioselective catalysis
Takizawa, S.; Jayaprakash, D.; Patil, M. L.; Muthiah, C.; Sasai, H. Materials Integration 2004, 17, 3-6.

10. Development of novel immobilization methods for multifunctionl asymmetric catalysts
Takizawa, S.; Sasai, H. 生産と技術 2004, 56, 43.

11. Trend in the development of novel chiral ionic liquids
Patil, M. L.; Takizawa, S.; Sasai, H. Chemical Industry 2004, 55, 877.

12. スピロビスイソオキサゾリン配位子（SPRIXs）の創製と触媒的不斉合成ヘの応用
荒井緑, 篠原俊夫, 荒井孝義, 笹井宏明 有機合成化学協会誌 2004, 62, 59.

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2003

Original Paper

1. Design and Synthesis of Novel Spiro Pyridinium and Quinolinium Salts
Patil, M. L.; Takizawa, S.; Sasai, H. Heterocycles 2003, 61, 581.

2. Metal-bridged Polymers as Insoluble Multicomponent Asymmetric Catalysts with High Enantiocontrol: An Approach for the Immobilization of Catalysts without Using any Support
Takizawa, S.; Somei, H.; Jayaprakash, D.; Sasai, H. Angew. Chem. Int. Ed. 2003, 42, 5711. (DOI)

3. Monolayer-protected Au Cluster (MPC)-supported Ti-BINOLate Complex
Marubayashi, K.; Takizawa, S.; Kawakusu, T.; Arai, T.; Sasai, H. Org. Lett. 2003, 5, 4409. (DOI)

4. Synthesis of Novel Chiral Spiro Bis(pyrazole) Ligands
Takizawa, S.; Honda, Y.; Arai, M. A.; Kato, T.; Sasai, H. Heterocycles 2003, 60, 2551.

5. Polymer Supported BisBINOL Ligands for the Immobilization of Multicomponent Asymmetric Catalysts
Sekiguti, T.; Iizuka, Y.; Takizawa, S.; Jayaprakash, D.; Arai, T.; Sasai, H. Org. Lett. 2003, 5, 2647. (DOI)

6. Enantioselective Synthesis of a-Methylene-g-butyrolactones Using Chiral Pd(II)-SPRIX Catalyst
Muthiah, C.; Arai, M. A.; Shinohara, T.; Arai, T.; Takizawa, S.; Sasai, H. Tetrahedron Lett. 2003, 44, 5201. (DOI)

7. Enantioselective Epoxidation of a,b-Unsaturated Ketons Using Polymer-supported Lanthanoid-BINOL Complexes
Jayaprakash, D.; Kobayashi, Y.; Watanabe, S.; Arai, T.; Sasai, H. Tetrahedron: Asymmetry 2003, 14, 1587. (DOI)

8. Catalytic Asymmetric Epoxidation of a,b-Unsaturated Ketons Using Polymeric BINOL
Jayaprakash, D.; Kobayashi, Y.; Arai, T.; Hu, Q.-S.; Zheng, X.-F.; Pu, L.; Sasai, H. J. Mol. Catal. A: Chem. 2003, 196, 145. (DOI)

9. "Catalyst Analogue": A Concept for Constructing Multicomponent Asymmetric Catalysts (MAC) Using a Polymer Support
Arai, T.; Sekiguti, T.; Otsuki, K.; Takizawa, S.; Sasai, H. Angew. Chem. Int. Ed. 2003, 42, 2144. (DOI)

10. Synthesis of New Chiral Bis(isoxazoline) Ligands Containing Spiro[5.5]undecane Skeleton
Arai, M. A.; Kuraishi, M.; Arai, T.; Sasai, H. Chirality 2003, 15, 101. (DOI)

11. The First Enantioselective Intramolecular Amino-carbonylation of Alkynes Promoted by Pd(II)-Spiro Bis(isoxazoline) Catalyst
Shinohara, T.; Arai, M. A.; Wakita, K.; Arai, T.; Sasai, H. Tetrahedron Lett. 2003, 44, 711. (DOI)

12. Synthesis and Character of New Bis(isoxazoline) Ligands
Shinohara, T.; Wakita, K.; Arai, M. A.; Arai, T.; Sasai, H. Heterocycles 2003, 59, 587.

13. The Catalytic Activities of Nanoclusters Dispersed on Apatite
Ichihara, J.; Iteya, K.; Kawaguchi, H.; Sasaki, Y.; Nakayama, H.; Yamaguchi, S. J. Ceram. Process. Res. 2003, 4, 42.

14. Cetylpyridinium Dodecatungstate on Fluorapatite: Efficient and Reusable Solid Catalyst for Solvent-Free Epoxidation
Ichihara, J.; Kambara, A.; Iteya, K.; Sugimoto, E.; Shinkawa, T.; Takaoka, A.; Yamaguchi, S.; Sasaki, Y. Green Chem. 2003, 5, 491.

15. New Approach to Environmentally Benign Epoxidation: The Solid-Phase-System Using Urea-H2O2 and Recyclable Dodecatungstate on Apatite
Ichihara, J.; Iteya, K.; Kambara, A.; Sasaki, Y. Catal. Today 2003, 87, 163.

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