The Institute of Scientific and Industrial Research, Osaka University

ISIR OSAKA UNIVERSITY

Division of Biological and Molecular Sciences

Department of Complex Molecular Chemistry

Staff

Y.HIGUCHI
  • Assis. Prof.
    Y.HIGUCHI

Content of research

Based on chemical proteomic approaches, our research interests are focused on the rational design and synthesis of small organic compounds that potentially modulate protein-protein interactions. These compounds are also utilized as a tool in our chemical genomic study to elucidate intracellular signaling pathways.

Current Research Programs

  • 1. Drug discovery based on controlling intracellular signal transductions by small molecues.
    2. Design and synthesis of inhibitors for bacterial efflux pumps.
    3. Design and synthesis of bioactive lipids as probe molecues for chemical biology and development of the lipid transport acivity monioring system.

Figure / Graph

ジテルペン配糖体をリードとする新規抗がん剤の開発
  • Anti-cancer agents based on natural diterpene glycosides
新規核酸塩基を利用したウイルスゲノム配列の目視診断
  • Identification of virus genome using novel type of nucleobases

VIDEO INTRODUCTION