(66) Photoswitchable molecular glue for RNA: reversible photocontrol of structure and function of the ribozyme, Dohno, C.; Kimura, M.; Fujiwara, Y.; Nakatani, K. Nucleic Acids Res. 2023, 51, 9533-9541. DOI: 10.1093/nar/gkad690.

(65) Unique Crosslinking Properties of Psoralen-conjugated Oligonucleotides developed by Novel Psoralen N-Hydroxysuccinimide Esters, Nakao, J.; Mikame, Y.; Eshima, H.; Yamamoto, T.; Dohno, C.; Wada, T.; Yamayoshi, A. ChemBioChem 2023, 24, e202200789. DOI: 10.1002/cbic.202200789.

(64) Synthesis and Evaluation of Oligonucleotide-Containing 2'-O-{[(4,5',8-trimethylpsoralen)-4'-ylmethoxy]ethylaminocarb-onyl}adenosine as Photo-crosslinkable Gene Targeting Tools, Mikame, Y.; Sakai, Y.; Tahara, R.; Doi, K.; Yamamoto, T.; Dohno, C.; Shibata, T.; Yamayoshi, A. Chem. Pharm. Bull. 2022, 70, 726-730. DOI: 10.1248/cpb.c22-00333.

(63) Premature translation termination mediated non-ER stress induced ATF6 activation by a ligand-dependent ribosomal frameshifting circuit, Hsu, H. T.; Murata, A.; Dohno, C.; Nakatani, K.; Chang, K. Nucleic Acids Res. 2022, 50, 5369-5383. doi.org/10.1093/nar/gkac257.

(62) HT-SELEX based identification of binding pre-miRNA hairpin-motif for small molecule, Mukherjee, S.; Murata, A.; Ishida, R.; Sugai, A.; Dohno, C.; Hamada, M.; Krishna, S.; Nakatani, K. Mol. Ther. Nucleic Acids 2022, 27, 165-174. doi.org/10.1016/j.omtn.2021.11.021.

(61) Short Tandem Repeat Contractions during in vitro DNA Synthesis by Repeat-Binding Molecules, Hagihara, M.; Dohno, C.; Saito, K.; Sugimoto, K.; Hishinuma, Y.; Sohma, Y.; Shibata, T.; Nakatani, K. Chem. Lett. 2021, 50, 1848-1851. doi:10.1246/cl.210415.

(60) Cyclic mismatch binding ligands interact with disease-associated CGG trinucleotide repeats in RNA and suppress their translation, Konieczny, P.; Mukherjee, S.; Stepniak-Konieczna, E.; Taylor, K.; Niewiadomska, D.; Piasecka, A.; Walczak, A.; Baud, A.; Dohno, C.; Nakatani, K.; Sobczak, K. Nucleic Acids Res. 2021, 49, 9479-9495. doi.org/10.1093/nar/gkab669.

(59) Rational Design of a Photoswitchable DNA Glue Enabling High Regulatory Function and Supramolecular Chirality Transfer, Simeth, N.; Kobayashi, S.; Kobauri, P.; Crespi, S.; Szymański, W.; Nakatani, K.; Dohno, C.; Feringa, B. Chem. Sci. 2021, 12, 9207-9220. DOI: 10.1039/D1SC02194J.

(58) Small molecule-induced trinucleotide repeat contractions during in vitro DNA synthesis, Dohno, C.; Hagihara, M.; Binti Mohd Zaifuddin, N.; Nihei, M.; Saito, K.; Nakatani, K. Chem. Commun. 2021, 57, 3235-3238. DOI: 10.1039/D1CC00349F.

(57) The dimeric form of 1,3‐diaminoisoquinoline derivative rescued the mis‐splicing of Atp2a1 and Clcn1 genes in myotonic dystrophy type 1 mouse model, Matsumoto, J.; Nakamori, M.; Okamoto, T.; Murata, A.; Dohno, C.; Nakatani, K. Chem. Eur. J. 2020, 26, 14305-14309. doi: 10.1002/chem.202001572.

(56) Recognition of expanded GGGGCC hexanucleotide repeat by synthetic ligand through interhelical binding, Lu, Y.; Dohno, C.; Nakatani, K. Biochem. Biophys. Res. Commun. 2020, 531, 56-61. doi: 10.1016/j.bbrc.2020.03.107.

(55) Novel Naphthyridine Tetramer that Recognizes Tandem G−G Mismatches by Formation of Interhelical Complex, Lu, Y.; Dohno, C.; Nakatani, K. Chem. Commun. 2020, 56, 754-757. 10.1039/C9CC08111A.

(54) Structural insights into synthetic ligands targeting A−A pairs in disease-related CAG RNA repeats, Mukherjee, S.; Błaszczyk, L.; Rypniewski, W.; Falschlunger, C.; Micura, R.; Murata, A.; Dohno, C.; Nakatani, K.; Kiliszek, A. Nucl. Acids Res. 2019, 47, 10906-10913. doi.org/10.1093/nar/gkz832.

(53) Molecular glue for RNA: Regulating RNA structure and function through a synthetic RNA binding molecule. Dohno, C.; Nakatani, K. ChemBioChem 2019, 20, 2903-2910. doi: 10.1002/cbic.201900223.

(52) A dimeric 2,9-diamino-1,10-phenanthroline derivative improves alternative splicing in myotonic dystrophy type 1 cell and mouse models. Li, J.; Nakamori, M.; Matsumoto, J.; Murata, A.; Dohno, C.; Kiliszek, A.; Taylor, K.; Sobczak, K.; Nakatani, K. Chem. Eur. J. 2018, 24, 18115-18122. 10.1002/chem.201804368.

(51) Restoration of Ribozyme Tertiary Contact and Function by Using a Molecular Glue for RNA. Dohno, C.; Kimura, M.; Nakatani, K. Angew. Chem. Int. Ed. 2018, 57, 506-510, DOI: 10.1002/anie.201709041.

(50) Design and synthesis of cyclic mismatch binding ligands (CMBLs) with variable linkers by ring closing metathesis and their photophysical and DNA repeat binding properties, Mukherjee, S.; Dohno, C.; Nakatani, K. Chem. Eur. J. 2017, 23, 11385-11396, DOI: 10.1002/chem.201702064.

(49) Amphiphilic DNA tiles for controlled insertion and 2D assembly on fluid lipid membranes: Effect on mechanical properties, Dohno, C.; Makishi, S.; Nakatani, K.; Contera, S. Nanoscale. 2017, 9, 3051-3058. DOI: 10.1039/C6NR07084A.

(48) A Ligand that Targets CUG Trinucleotide Repeats, Li. J.; Matsumoto, J.; Bai, L.-P.; Murata, A.; Dohno, A.; Nakatani, K. Chem. Eur. J. 2016, 22, 14881-14889. doi: 10.1002/chem.201602741. selected as cover picture.

(47) Cyclic mismatch binding ligand CMBL4 binds to the 5'-T-3'/5'-GG-3' site by inducing the flipping out of thymine base, Mukherjee, S.; Dohno, C.; Asano, K.; Nakatani, K. Nucl. Acids Res. 2016, 44, 7090-7099. doi: 10.1093/nar/gkw672.

(46) Synthesis of 1H-pyrrolo[3,2-h]quinoline-8-amine derivatives that target CTG trinucleotide repeats, Matsumoto, J.; Li, J.; Dohno, C.; Nakatani, K. Bioorg. Med. Chem. Lett. 2016, 26, 3761-3764. doi:10.1016/j.bmcl.2016.05.062.

(45) Naphthyridine-Benzoazaquinolone: Evaluation of tricyclic system for the binding to (CAG)n Repeat DNA and RNA, Li, J.; Sakata, A.; He, H.; Bai, L.-P.; Murata, A.; Dohno, C.; Nakatani, K. Chem. Asian. J. 2016, 11, 1971-1981. doi: 10.1002/asia.201600527.

(44) A hybridisation-dependent membrane-insertable amphiphilic DNA, Dohno, C.; Matsuzaki, K.; Yamaguchi, H.; Shibata, T.; Nakatani, K. Org. Biomol. Chem. 2015, 13, 10117-10121. doi: 10.1039/C5OB01761K.

(43) 2-Aminophenanthroline dimer stabilized the C-C mismatched duplex DNA, Li, J.; Matsumoto, J. Otabe, T.; Dohno, C.; Nakatani, K. Bioorg. Med. Chem. 2015, 23, 753-758. doi: 10.1016/j.bmc.2014.12.062.

(42) Cytosine-bulge dependent fluorescence quenching for real-time hairpin primer PCR, Takei, F.; Chen, X.; Yu, G.; Shibata, T.; Dohno, C.; Nakatani, K. Chem. Commun. 2014, 50, 15195-15198. doi: 10.1039/c4cc06780k.

(41) Modulation of binding properties of amphiphilic DNA containing multiple dodecyl phosphotriester linkages to lipid bilayer membrane, Makishi, S.; Shibata, T.; Okazaki, M.; Dohno, C.; Nakatani, K. Bioorg. Med. Chem. Lett., 2014, 24, 3578-3581. doi: 10.1016/j.bmcl.2014.05.042.

(40) Formation of Ligand-Assisted Complex of Two RNA Hairpin Loops, Hong, C.; Otabe, T.; Matsumoto, S.; Dohno, C.; Murata, A.; Hagihara, M.; Nakatani, K. Chem. Eur. J., 2014, 20, 5244-5252.

(39) A synthetic riboswitch that operates using a rationally designed ligand-RNA pair. Dohno, C.; Kohyama, I.; Kimura, M.; Hagihara, M.; Nakatani, K. Angew. Chem. Int. Ed. 2013, 52, 9976-9979.

(38) G-quadruplex formation of entirely hydrophobic DNA in organic solvents. Shibata, T.; Dohno, C.; Nakatani, K. Chem. Commun. 2013, 49, 5501-5503.

(37) Ligand-induced electron spin-assembly on a DNA tile. Atsumi, H.; Nakazawa, S.; Dohno, C.; Sato, K.; Takui, T.; Nakatani, K. Chem. Commun. 2013, 49, 6355-6458. Front Cover.

(36) Triethynylmethane: A Molecular Unit Inducing Excimer-Like Emission in Aggregated States of Hydrocarbon Fluorophores. Otabe, T.; Matsumoto, S.; Nakagawa, H.; Hong, C.; Dohno, C.; Nakatani, K. Tetrahedron. Lett. 2013, 54, 143-146.

(35) Assembly of a small DNA rectangular parallelepiped block into higher order nanostructures. Nakagawa, H.; Toda, M.; Atsumi, H.; Hagihara, M.; Hayashi-Nishino, M.; Dohno, C.; Nakatani, K. Chem. Lett. 2012, 41, 1550-1552.

(34) Amphiphilic DNA duplex stabilized by hydrophobic zipper. Dohno, C.; Shibata, T.; Okazaki, M.; Makishi, S.; Nakatani, K. Eur. J. Org. Chem. 2012, 5317-5323.

(33) Naphthyridine tetramer with a preorganized structure for 1:1 binding to a CGG/CGG sequence. Dohno, C.; Kohyama, I.; Hong, C.; Nakatani, K. Nucleic. Acids. Res. 2012, 40, 2771-2781.

(32) Interstrand Cross-Link for Discrimination of Methylated Cytosines. Dohno, C.; Shibata, T.; Nakatani, K. Chem. Lett. 2011, 40, 852-854.

(31) Control of DNA hybridization by photoswitchable molecular glue, Dohno, C.; Nakatani, K. Chem. Soc. Rev. 2011, 40, 5718-5729.

(30) Molecular-Glue-Triggered DNA Assembly to Form a Robust and Photoresponsive Nano-Network, Wang, C.; Pu, F.; Lin, Y.; Ren, J.; Dohno, C.; Nakatani K.; Qu, X. Chem. Eur. J. 2011, 17, 8189-8197.

(29) Ligand Inducible Assembly of a DNA Tetrahedron. Dohno, C.; Atsumi, H.; Nakatani, K. Chem. Commun. 2011, 47, 3499-3501.

(28) Discrimination of N6-methyl adenine in a specific DNA sequence. Dohno, C.; Shibata, T.; Nakatani, K. Chem. Commun. 2010, 46, 5530-5532.

(27) A Light-Driven, Supramolecular Optical Switch, Uno, S.; Dohno, C.; Bittermann, H.; Malinovskii, V. L.; Häner, R.; Nakatani, K. Angew. Chem. Int. Ed. 2009, 48, 7362-7365.

(26) Photoswitchable Unsymmetrical Ligand for DNA Hetero-Mismatches, Dohno, C.; Yamamoto, T.; Nakatani, K. Eur. J. Org. Chem. 2009, 4051-4058.

(25) The effect of linker length on binding affinity of a photoswitchable molecular glue for DNA, Dohno, C.; Uno, S.; Sakai, S.; Oku, M.; Nakatani, K. Bioorg. Med. Chem. 2009, 17, 2536-2543.

(24) Synthesis of Dimeric 2-Amino-1,8-naphthyridine and Related DNA-Binding Molecules, Nakatani, K.; He, H.; Uno, S.; Yamamoto, T.; Dohno, C. Current Protocols in Nucleic Acid Chemistry 2008, Unit 8.6, 1-21.

(23) Photoswitchable Molecular Glue for DNA, Dohno, C.; Uno, S.; Nakatani, K. J. Am. Chem. Soc. 2007, 129, 11898-11899.

(22) Photoregulation of a Peptide-RNA Interaction on a Gold Surface, Hayashi, G.; Hagihara, M.; Dohno, C.; Nakatani, K. J. Am. Chem. Soc. 2007, 129, 8678-8679.

(21) Bidirectional Control of Gold Nanoparticle Assembly by Turning On and Off DNA Hybridization with Thermally Degradable Molecular Glue, Peng, T.; Dohno, C.; Nakatani, K. ChemBioChem 2007, 8, 483−485.

(20) Highly selective fluorescent nucleobases for designing base-discriminating fluorescent probes Saito, I.; Saito, Y.; Hanawa, K.; Hayashi, K.; Motegi, K.; Bag, S. S.; Dohno, C.; Ichiba, T.; Tainaka, K.; Okamoto, A. Pure Appl. Chem. 2006, 78 (12), 2305−2312.

(19) Mismatch binding ligands function as molecular glue of DNA, Peng, T.; Dohno, C.; Nakatani, K. Angew. Chem. Int. Ed. 2006, 45, 5623−5626.

(18) Efficient DNA Alkylation by a Pyrrole-Imidazole CBI Conjugate with an Indole Liker: Sequence-Specific Alkylation with Nine-Base-Pair Recognition, Bando, T.; Sasaki, S.; Minoshima, M.; Dohno, C.; Shinohara, K.; Narita, A.; Sugiyama, H. Bioconjugate Chem. 2006, 17, 715−720.

(17) Stable, Specific and Reversible Base Pairing via Schiff Base. Dohno, C.; Okamoto, A.; Saito, I. J. Am. Chem. Soc. 2005, 127, 16681−16684.

(16) Discrimination of Single Nucleotide Alterations Based on G-Specific Fluorescence Quenching Dohno, C.; Saito, I. ChemBioChem. 2005, 6, 1075−1081.

(15) Effects of the Photooxidant on DNA-Mediated Charge Transport Williams, T. T.; Dohno, C.; Stemp, E. D. A.; Barton, J. K. J. Am. Chem. Soc. 2004, 126, 8148−8158.

(14) Chemical Evidence for Charge Transfer between Photoexcited 2-Aminopurine and Guanine in Duplex DNA O’Neill, M. A.; Dohno, C.; Barton, J. K. J. Am. Chem. Soc. 2004, 126, 1316−1317.

(13) Fast Back Electron Transfer Prevents Guanine Damage by Photoexcited Thionine Bound to DNA Dohno, C.; Stemp, E. D. A.; Barton, J. K. J. Am. Chem. Soc. 2003, 125, 9586−9587.

(12) Hole Trapping at N6-Cyclopropyldeoxyadenosine Suggests a Direct Contribution of Adenine Bases to Hole Transport through DNA, Dohno, C.; Ogawa, A.; Nakatani, K.; Saito, I. J. Am. Chem. Soc. 2003, 125, 10154−10155.

(11) Guanine of the Third Strand of C.G*G Triplex Serves as an Effective Hole Trap, Dohno, C.; Nakatani, K.; Saito, I. J. Am. Chem. Soc. 2002, 124, 14580−14585.

(10) N2-Phenyldeoxyguanosine: Modulation of the Chemical Property of Deoxyguanosine toward One Electron Oxidation in DNA, Nakatani, K.; Dohno, C.; Saito, I. J. Am. Chem. Soc. 2002, 124, 6802−6803.

(9) Suppression of DNA-Mediated Charge Transport by BamH I Binding, Nakatani, K.; Dohno, C.; Ogawa, A.; Saito, I. Chem. Biol. 2002, 9, 361−366.

(8) Modulation of remote DNA oxidation by hybridization with peptide nucleic acids (PNA) Okamoto, A.; Tanabe, K.; Dohno, C.; Saito, I. Bioorg. Med. Chem. 2002, 10, 713−718.

(7) Design of Hole-Trapping Nucleobase: Termination of DNA Mediated Hole Transport at N2-Cyclopropyldeoxyguanosine, Nakatani, K.; Dohno, C.; Saito, I. J. Am. Chem. Soc. 2001, 123, 9681−9682.

(6) Site Selective Generation of Guanine Cation Radical inDuplex DNA: Modulation of the Direction of Hole Transport, Nakatani, K.; Dohno, C.; Saito, I. Tetrahedron Lett. 2000, 41, 10041−10045.

(5) Modulation of DNA-Mediated Hole Transport Efficiency by Changing Superexchange Electronic Interaction, Nakatani, K.; Dohno, C.; Saito, I. J. Am. Chem. Soc. 2000, 122, 5893−5894.

(4) Chemistry of Sequence Dependent Remote Guanine Oxidation: Photoreaction of Duplex DNA containing Cyanobenzophenone Substituted Uridine, Nakatani, K.; Dohno, C.; Saito, I. J. Am. Chem. Soc. 1999, 121, 10854−10855.

(3) Synthesis of DNA Oligomers Containing Modified Uracil Possessing Electron-Accepting Benzophenone Chromophore, Nakatani. K.; Dohno, C.; Saito, I. J. Org. Chem. 1999, 64, 6306−6311.

(2) p-Cyano Substituted 5-Benzoyldeoxyuridine as a Novel Electron-Accepting Nucleobase for One-Electron Oxidaiton of DNA, Nakatani, K.; Fujisawa, K.; Dohono, C.; Nakamura, C.; Saito, I. Tetrahedron Lett. 1998, 39, 5995−5998.

(1) p-Cyano Substituted Benzophenone as an Excellent Photophore for One-Electron Oxidation of DNA, Nakatani, K.; Dohno, C.; Nakamura, T.; Saito, I. Tetrahedron Lett. 1998, 39, 2779−2782.

(4) Dohno, C.; Nakatani, K. Non-Covalent Modification of Double Stranded DNA at the Mismatch and Bulged Site. In Modified Nucleic Acids; Nakatani, K.; Tor, Y., Eds.; Springer International Publishing AG Switzerland, 2016, 31, 189−207.

(3) DNAの光電子移動の制御 堂野主税、 ゲノム化学、化学同人、2007, 127−133.

(2) Charge Transfer in DNA: From Mechanism to Application Chapter 7 (153−174), Chemical Approach to Modulating Hole Transport Through DNA. Dohno, C.; Saito, I. (Wiley-VCH Verlag GmbH & KGaA, Weinheim, 2005)

(1) DNAを媒体とする電荷移動 中谷和彦、堂野主税、齋藤烈、 光化学、2001, 32, 129−135.

(10) Reversible regulation of binding between a photoresponsive peptide and its RNA aptamer. Hayashi, G., Hagihara, M., Dohno, C., Nakatani, K. Nucleic Acids Symp. Ser., 2007, 51, 93−94.

(9) Reversible control of DNA hybridization by photoresponsive ligands. Uno, S.N., Dohno, C., Oku, M., Nakatani, K. Nucleic Acids Symp. Ser., 2007, 51, 173−174.

(8) Control of DNA hybridization by photoswitchable mismatch binding ligands. Dohno, C.; Uno, S.; Nakatani, K 33th symposium on Nucleic Acids Chemistry, (Oxford university press, Oxford, 2006) Nucleic Acids Symp. Ser., 2006, 50, 87−88.

(7) Schiff base-mediated base pairing Dohno, C.; Okamoto, A.; Saito, I. 32th symposium on Nucleic Acids Chemistry, (Oxford university press, Oxford, 2005) Nucleic Acids Symp. Ser., 2005, 49, 185−186.

(6) Base-Discriminating Fluorescent DNA Probe based on the guanine-specific fluorescence quenching Dohno, C.; Saito, I. 31th symposium on Nucleic Acids Chemistry, (Oxford university press, Oxford, 2004) Nucleic Acids Symp. Ser., 2004, 48, 93−94.

(5) Modulation of DNA-mediated hole transport efficiency by DNA-protein complex formation Dohno, C.; Nakatani, K.; Saito, I. 28th symposium on Nucleic Acids Chemistry, (Oxford university press, Oxford, 2001) Nucleic Acids Res. Suppl., 2001, 45, 15−16.

(4) Control of Electron Transfer in DNA by Peptide Nucleic Acids Tanabe, K.; Yoshida, K.; Dohno, C.; Okamoto, A.; Saito, I. 28th symposium on Nucleic Acids Chemistry, (Oxford university press, Oxford, 2000) Nucleic Acids Symp. Ser., 2000, 44, 35−36.

(3) Analysis of photoinduced electron-transfer reaction through the oligodeoxynucleotides containing cyanobenzophenone substituted 2'-deoxyuridine Dohno, C.; Nakatani, K.; Nakamura, T.; Fujisawa, K.; Saito, I. 25th symposium on Nucleic Acids Chemistry, (Oxford university press, Oxford, 1998) Nucleic Acids Symp. Ser., 1998, 39, 41−41.

(2) -GG- Specific Cleavage via Hole Hopping through Double-Stranded DNA Nakamura, T.; Dohno, C.; Nakatani, K.; Saito, I. 24th symposium on Nucleic Acids Chemistry, (Oxford university press, Oxford, 1997) Nucleic Acids Symp. Ser., 1997, 37, 87−88.

(1) Sequence- and Conformation-Dependent Photoinduced-Electron-Transfer from DNA Nakamura, T.; Sugiyama, H.; Fujisawa, K.; Dohno, C.; Nakatani, K.; Saito, I. 23th symposium on Nucleic Acids Chemistry, (Oxford university press, Oxford, 1996) Nucleic Acids Symp. Ser., 1996, 35, 89−90.