論文

• Hinuma S, Fujita K, Kuroda S.
  Specific Binding and Endocytosis of Liposomes to HEK293T Cells via Myrisoylated Pre-S1 Peptide Bound to Sodium Taurocholate Cotransporting Polypeptide.
  Vaccines (Basel). 2022 Nov 30;10(12):2050. [link]
• Iijima M, Kawaguchi A, Ogura Y, Yoshimoto R, Kaneda M, Kera K, Kuroda S, Nakayama T.
  Nano-visualization of the in vitro antiviral activity of black tea based on production area using a liposome-based virus membrane model.
  Biosci Biotechnol Biochem. 2022 Nov 23;86(12):1658-1669. [link]
• Yasunaga M, Takai E, Hattori S, Tatematsu K, Kuroda S.
  Effects of 3-octen-2-one on human olfactory receptor responses to vanilla flavor.
  Biosci Biotechnol Biochem. 2022 Oct 20;86(11):1562-1569. [link]
• Yamagishi A, Mizusawa M, Uchida K, Iijima M, Kuroda S, Fukazawa K, Ishihara K, Nakamura C.
  Mechanical detection of interactions between proteins related to intermediate filament and transcriptional regulation in living cells.
  Biosens Bioelectron. 2022 Nov 15;216:114603. [link]
• Somiya M, Kuroda S.
  Engineering of Extracellular Vesicles for Small Molecule-Regulated Cargo Loading and Cytoplasmic Delivery of Bioactive Proteins.
  Mol Pharm. 2022 Jul 4;19(7):2495-2505. [link]
• Hinuma S, Kuroda S.
  Binding of Hepatitis B Virus Pre-S1 Domain-Derived Synthetic Myristoylated Peptide to Scavenger Receptor Class B Type 1 with Differential Properties from Sodium Taurocholate Cotransporting Polypeptide.
  Viruses. 2022 Jan 7;14(1):105. [link]
• Iijima M, Yamada Y, Nakano H, Nakayama T, Kuroda S.
  Bio-nanocapsules for oriented immobilization of DNA aptamers on aptasensors.
  Analyst. 2022 Jan 31;147(3):489-495. [link]
• Murakawa T, Suzuki M, Fukui K, Masuda T, Sugahara M, Tono K, Tanaka T, Iwata S, Nango E, Yano T, Tanizawa K, Okajima T.
  Serial femtosecond X-ray crystallography of an anaerobically formed catalytic intermediate of copper amine oxidase.
  Acta Crystallogr D Struct Biol. 2022 Dec 1;78(Pt 12):1428-1438. [link]
• Shoji M, Murakawa T, Nakanishi S, Boero M, Shigeta Y, Hayashi H, Okajima T.
  Molecular mechanism of a large conformational change of the quinone cofactor in the semiquinone intermediate of bacterial copper amine oxidase.
  Chem Sci. 2022 Aug 23;13(36):10923-10938. [link]
• Pasqua M, Coluccia M, Eguchi Y, Okajima T, Grossi M, Prosseda G, Utsumi R, Colonna B.
  Roles of Two-Component Signal Transduction Systems in Shigella Virulence.
  Biomolecules. 2022 Sep 18;12(9):1321. [link]
• Murakawa T, Kurihara K, Adachi M, Kusaka K, Tanizawa K, Okajima T.
  Re-evaluation of protein neutron crystallography with and without X-ray/neutron joint refinement.
  IUCrJ. 2022 Apr 8;9(Pt 3):342-348. [link]
• Sun-Wada GH, Wada Y.
  Exploring the Link between Vacuolar-Type Proton ATPase and Epithelial Cell Polarity.
  Biol Pharm Bull. 2022;45(10):1419-1425. [link]
• Sun-Wada GH, Wada Y.
  The a subunit isoforms of vacuolar-type proton ATPase exhibit differential distribution in mouse perigastrulation embryos.
  Sci Rep. 2022 Aug 10;12(1):13590. [link]
• Matsumoto N, Sekiya M, Sun-Wada GH, Wada Y, Nakanishi-Matsui M.
  The lysosomal V-ATPase a3 subunit is involved in localization of Mon1-Ccz1, the GEF for Rab7, to secretory lysosomes in osteoclasts.
  Sci Rep. 2022 May 19;12(1):8455. [link]
• Somiya M.
  Comment on "Cutting Edge: Circulating Exosomes with COVID Spike Protein Are Induced by BNT162b2 (Pfizer-BioNTech) Vaccination prior to Development of Antibodies: A Novel Mechanism for Immune Activation by mRNA Vaccines".
  J Immunol. 2022 Apr 15;208(8):1833. [link]
• Horie M, Yamano-Adachi N, Kawabe Y, Kaneoka H, Fujita H, Nagamori E, Iwai R, Sato Y, Kanie K, Ohta S, Somiya M, Ino K.
  Recent advances in animal cell technologies for industrial and medical applications.
  J Biosci Bioeng. 2022 Jun;133(6):509-514. [link]
• 黒田俊一
  ヒト嗅覚受容体発現セルアレイセンサーでなければ解決できない匂い課題について
  月刊せんい2022 75(11)611-618
  
• Iijima M, Kuroda S
  Chapter 11　Oriented immobilization of biomolecules on small surfaces
  Academic Press, Elsevier (2022) pp249-268
  Biocatalyst Immibolization: Foundations and Applications (Ed. Dr. Maria Lujan Ferreira)
  Foundations and Frontiers in Enzymology Series (Series Ed. Munishwar Nath Gupta)
  
• 黒田俊一，立松健司　
  技術情報協会2022 第６章 機器分析・センサ全般 問５ ヒト嗅覚受容体発現セルアレイセンサとは？
  

総説

著書

▲ ページ上部へ

論文

• Somiya M, Kuroda S.
  Reporter gene assay for membrane fusion of extracellular vesicles.
  J Extracell Vesicles. 2021 Nov;10(13):e12171. [link]
• Hinuma S, Fujita K, Kuroda S.
  Binding of Nanoparticles Harboring Recombinant Large Surface Protein of Hepatitis B Virus to Scavenger Receptor Class B Type 1.
  Viruses. 2021 Jul 10;13(7):1334. [link]
• Nanahara M, Chang YT, Somiya M, Kuroda S.
  HBV Pre-S1-Derived Myristoylated Peptide (Myr47): Identification of the Inhibitory Activity on the Cellular Uptake of Lipid Nanoparticles.
  Viruses. 2021 May 17;13(5):929. [link]
• Takagi K, Somiya M, Jung J, Iijima M, Kuroda S.
  Polymerized Albumin Receptor of Hepatitis B Virus for Evading the Reticuloendothelial System.
  Pharmaceuticals (Basel). 2021 Apr 25;14(5):408. [link]
• Koide N, Fujita K, Kuroda S, Hinuma S.
  Binding of liposomes composed of phosphatidylcholine to scavenger receptor class B type 1 and its modulation by phosphatidic acid in HEK293T cells.
  Biochim Biophys Acta Mol Cell Res. 2021 Jun;1868(7):119043. [link]
• Ito J, Minemura T, Wälchli S, Niimi T, Fujihara Y, Kuroda S, Takimoto K, Maturana AD.
  Id2 Represses Aldosterone-Stimulated Cardiac T-Type Calcium Channels Expression.
  Int J Mol Sci. 2021 Mar 30;22(7):3561. [link]
• Somiya M, Kuroda S.
  Real-Time Luminescence Assay for Cytoplasmic Cargo Delivery of Extracellular Vesicles.
  Anal Chem. 2021 Apr 6;93(13):5612-5620. [link]
• Oozeki T, Nakai T, Kozakai K, Okamoto K, Kuroda S, Kobayashi K, Tanizawa K, Okajima T.
  Functional and structural characterization of a flavoprotein monooxygenase essential for biogenesis of tryptophylquinone cofactor.
  Nat Commun. 2021 Feb 10;12(1):933. [link]
• Li H, Somiya M, Kuroda S.
  Enhancing antibody-dependent cellular phagocytosis by Re-education of tumor-associated macrophages with resiquimod-encapsulated liposomes.
  Biomaterials. 2021 Jan;268:120601. [link]
• Murakawa T, Suzuki M, Arima T, Sugahara M, Tanaka T, Tanaka R, Iwata S, Nango E, Tono K, Hayashi H, Fukui K, Yano T, Tanizawa K, Okajima T.
  Microcrystal preparation for serial femtosecond X-ray crystallography of bacterial copper amine oxidase.
  Acta Crystallogr F Struct Biol Commun. 2021 Oct 1;77(Pt 10):356-363. [link]
• Nakai T, Tanizawa K, Okajima T.
  Eight genes are necessary and sufficient for biogenesis of quinohemoprotein amine dehydrogenase.
  Biosci Biotechnol Biochem. 2021 Aug 25;85(9):2026-2029. [link]
• Inada S, Okajima T, Utsumi R, Eguchi Y.
  Acid-Sensing Histidine Kinase With a Redox Switch.
  Front Microbiol. 2021 May 20;12:652546. [link]
• Sun-Wada GH, Tabata H, Wada Y.
  Vacuolar-type proton ATPase is required for maintenance of apicobasal polarity of embryonic visceral endoderm.
  Sci Rep. 2021 Sep 29;11(1):19355. [link]
• Matsumoto N, Sekiya M, Fujimoto Y, Haga S, Sun-Wada GH, Wada Y, Nakanishi-Matsui M.
  Functional complementation of V-ATPase a subunit isoforms in osteoclasts.
  J Biochem. 2021 Apr 29;169(4):459-466. [link]
• Somiya M, Mine S, Yasukawa K, Ikeda S.
  Sex differences in the incidence of anaphylaxis to LNP-mRNA COVID-19 vaccines.
  Vaccine. 2021 Jun 8;39(25):3313-3314. [link]
• 黒田俊一
  ヒト嗅覚受容体反応に基づく新しい創香技術
  化学 2021 76(11) 20-22
  
• 七原匡哉，浅井，立松健司，黒田俊一
  ヒト嗅覚官能を再現するヒト嗅覚受容体発現細胞アレイセンサーの開発
  食品と容器 2021 VOL.62 NO.10 635-641
  
• 黒田俊一
  においビジネス
  テクノロジー・ロードマップ20222031全産業編(2021) 484-487
  

総説

著書

▲ ページ上部へ

論文

• Kim H, Ishibashi K, Iijima M, Kuroda S, Nakamura C.
  Influence of Nivolumab for Intercellular Adhesion Force between a T Cell and a Cancer Cell Evaluated by AFM Force Spectroscopy.
  Sensors (Basel). 2020 Oct 8;20(19):5723. [link]
• Fujita K, Koide N, Somiya M, Kuroda S, Hinuma S.
  A regulatory role of scavenger receptor class B type 1 in endocytosis and lipid droplet formation induced by liposomes containing phosphatidylethanolamine in HEK293T cells.
  Biochim Biophys Acta Mol Cell Res. 2021 Jan;1868(1):118859. [link]
• Arima A, Tsutsui M, Yoshida T, Tatematsu K, Yamazaki T, Yokota K, Kuroda S, Washio T, Baba Y, Kawai T.
  Digital Pathology Platform for Respiratory Tract Infection Diagnosis via Multiplex Single-Particle Detections.
  ACS Sens. 2020 Nov 25;5(11):3398-3403. [link]
• Kim H, Hoshi M, Iijima M, Kuroda S, Nakamura C.
  Development of a universal method for the measurement of binding affinities of antibody drugs towards a living cell based on AFM force spectroscopy.
  Anal Methods. 2020 Jun 11;12(22):2922-2927. [link]
• Yoshimura K, Aoki H, Teruyama C, Iijima M, Tsutsumi H, Kuroda S, Hamano K.
  A Novel Hybrid Drug Delivery System for Treatment of Aortic Aneurysms.
  Int J Mol Sci. 2020 Aug 2;21(15):5538. [link]
• Iijima M, Yamada Y, Nakayama T, Kuroda S.
  Enhanced sugar chain detection by oriented immobilization of Fc-fused lectins.
  Biosci Biotechnol Biochem. 2020 Sep;84(9):1775-1779. [link]
• Somiya M, Kuroda S.
  Virus-mimicking nanocarriers for the intracellular delivery of therapeutic biomolecules.
  Nanomedicine (Lond). 2020 May;15(12):1163-1165. [link]
• Somiya M, Kuroda S.
  DDS Nanocarriers Mimicking Early Infection Machinery of Viruses.
  Yakugaku Zasshi. 2020;140(2):147-152. [link]
• Iijima M, Nakayama T, Kuroda S.
  Two-dimensional membrane scaffold for the oriented immobilization of biosensing molecules.
  Biosens Bioelectron. 2020 Feb 15;150:111860. [link]
• Shoji M, Murakawa T, Boero M, Shigeta Y, Hayashi H, Okajima T.
  Unique protonation states of aspartate and topaquinone in the active site of copper amine oxidase.
  RSC Adv. 2020 Oct 21;10(63):38631-38639. [link]
• Murakawa T, Kurihara K, Shoji M, Shibazaki C, Sunami T, Tamada T, Yano N, Yamada T, Kusaka K, Suzuki M, Shigeta Y, Kuroki R, Hayashi H, Yano T, Tanizawa K, Adachi M, Okajima T.
  Neutron crystallography of copper amine oxidase reveals keto/enolate interconversion of the quinone cofactor and unusual proton sharing.
  Proc Natl Acad Sci U S A. 2020 May 19;117(20):10818-10824. [link]
• Kinoshita-Kikuta E, Maruta S, Eguchi Y, Igarashi M, Okajima T, Utsumi R, Kinoshita E, Koike T.
  An immuno-dot blot assay for screening histidine kinase inhibitors.
  Anal Biochem. 2020 Jul 1;600:113765. [link]
• Okawa A, Hayashi M, Inagaki J, Okajima T, Tamura T, Inagaki K.
  Novel method for l-methionine determination using l-methionine decarboxylase and application of the enzyme for l-homocysteine determination.
  Biosci Biotechnol Biochem. 2020 May;84(5):927-935. [link]
• Kawamura N, Takaoka K, Hamada H, Hadjantonakis AK, Sun-Wada GH, Wada Y.
  Rab7-Mediated Endocytosis Establishes Patterning of Wnt Activity through Inactivation of Dkk Antagonism.
  Cell Rep. 2020 Jun 9;31(10):107733. [link]
• Matsumoto N, Matsukawa R, Takahashi S, Kudo K, Sun-Wada GH, Wada Y, Nakanishi-Matsui M.
  V-ATPase a3 isoform mutations identified in osteopetrosis patients abolish its expression and disrupt osteoclast function.
  Exp Cell Res. 2020 Apr 15;389(2):111901. [link]
• Somiya M.
  "Where does the cargo go?: Solutions to provide experimental support for the """"extracellular vesicle cargo transfer hypothesis."
  J Cell Commun Signal. 2020 Jun;14(2):135-146. [link]
• 曽宮正晴、黒田俊一
  バイオ医薬に利用されるキャリア開発：B型肝炎ウイルスの初期感染機構に基づくバイオナノカプセル
  DDS学会誌(2020) Vol 35 No. 1 57-63
• 曽宮正晴、黒田俊一
  バイオミミック技術によるウイルスの感染機構を搭載したDDSナノキャリアの開発
  薬学雑誌(2020) Vol 140 No. 2 14-152
• 佐藤翔、山﨑智子、立松健司、黒田俊一
  AIを活用したヒト嗅覚受容体応答の網羅的解析
  生産と技術(2020) Vol 72 No. 2 78-80

総説

著書

• Li H, Somiya M, Tatematsu K, Kuroda S.
  Construction of a Macrophage-Targeting Bio-Nanocapsule-Based Nanocarrier
  Methods Mol Biol. 2020;2059:299-313. [link]
• 江口陽子，岡島俊英，内海龍太郎
  環境応答　
  遺伝学の百科事典，丸善 （印刷中）

▲ ページ上部へ

論文

• Iijima M, Araki K, Liu Q, Somiya M, Kuroda S.
  Oriented immobilization to nanoparticles enhanced the therapeutic efficacy of antibody drugs.
  Acta Biomater. 86:373-380 (2019) [link]
• Fujita K, Somiya M, Kuroda S, Hinuma S.
  Induction of lipid droplets in non-macrophage cells as well as macrophages by liposomes and exosomes.
  Biochem Biophys Res Commun. 510(1):184-190 (2019). [link]
• Yamamoto N, Kashiwagi M, Ishihara M, Kojima T, Maturana AD, Kuroda S, Niimi T.
  Robo2 contains a cryptic binding site for neural EGFL-like (NELL) protein 1/2.
  J Biol Chem. 2019 Mar 22;294(12):4693-4703. [link]
• Kentaro Noi, Masumi Iijima, Shun'ichi Kuroda, Hirotsugu Ogi
  Ultrahigh-Sensitive Wireless QCM with Bio-nanocapsules
  "Sensors and Actuators B: Chemical　Volume 293, 15 August 2019, Pages 59-62" [link]
• Ayana Yamagishi, Moe Susaki, Yuta Takano, Mei Mizusawa, Mari Mishima, Masumi Iijima, Shun’ichi Kuroda, Tomoko Okada, Chikashi Nakamura
  The Structural Function of Nestin in Cell Body Softening is Correlated with Cancer Cell Metastasis
  "International Journal of Biological Sciences　Volume 15, Pages 1546-1556 (2019)" [link]
• Koizumi, Kaori; Nakamura, Hitomi; Iijima, Masumi; Matsuzaki, Takashi; Somiya, Masaharu; Kumasawa, Keiichi; Kimura, Tadashi; Kuroda, S.
  In vivo uterine local gene delivery system using TAT-displaying bionanocapsules
  Journal of Gene Medicine21 (12) e3140 (2019)
• Makusu Tsutsui, Tomoko Yamazaki, Kenji Tatematsu, Kazumichi Yokota, Yuko Esaki, Yukari Kubo, Hiroko Deguchi, Akihide Arima, Shun’ichi Kuroda and Tomoji Kawai
  High-throughput single nanoparticle detection using a feed-through channel-integrated nanopore
  Nanoscale 11 (43) 20475-20484 (2019)
• 曽宮正晴、黒田俊一
  エンベロープウイルスやエクソソームを利用したドラッグデリバリーシステムの開発
  "膜 (2019), Vol. 44. 222-227 "
• 佐藤翔、山崎智子、立松健司、黒田俊一
  ヒト嗅覚受容体センサーを駆使したAI調香師創生プロジェクトについて
  Aroma Research　20-4（2019）
• McGuire, C.M., Collins, M.P., Sun-Wada, G., Wada, Y., and Forgac, M
  Isoform-specific gene disruptions reveal a role for the V-ATPase subunit a4 isoform in the invasiveness of 4T1-12B breast cancer cells.
  "J Biol Chem 294, 11248-11258." [link]
• Ma, K., Bin, N.R., Shi, S., Harada, H., Wada, Y., Wada, G.H., Monnier, P.P., Sugita, S., and Zhang, L.
  Observations From a Mouse Model of Forebrain Voa1 Knockout: Focus on Hippocampal Structure and Function.
  "Front Cell Neurosci 13, 484." [link]
• Fujita K, Somiya M, Kuroda S and Hinuma S.
  Induction of lipid droplets in non-macrophage cells as well as macrophages by liposomes and exosomes.
  Biochemical and Biophysical Research Communications [link]
• Yoshitani K, Ishii E, Taniguchi K, Sugimoto H, Shiro Y, Akiyama Y, Kato A, Utsumi R, and Eguchi Y
  Identification of an internal cavity in the PhoQ sensor domain for PhoQ activity and SafA-mediated control.
  "Biosci. Biotechnol. Biochem. 83, 684-694 (2019)" [link]
• Kinoshita-Kikuta E, Kusamoto H, Ono S, Akiyama K, Eguchi Y, Igarashi M, Okajima T, Utsumi R, Kinoshita E, Koike T.
  Quantitative monitoring of His and Asp phosphorylation in a bacterial signaling system by using Phos-tag Magneta/Cyan fluorescent dyes
  "Electrophoresis. 40, 3005-3013 (2019)" [link]
• Tsutsui M, Yamazaki T, Tatematsu K, Yokota K, Esaki Y, Kubo Y, Deguchi H, Arima A, Kuroda S, Kawai T.
  High-throughput single nanoparticle detection using a feed-through channel-integrated nanopore.
  Nanoscale. 2019 Nov 21;11(43):20475-20484. [link]
• T. Murakawa, S. Baba, Y. Kawano, H. Hayashi, T. Yano, T. Kumasaka, M. Yamamoto, K. Tanizawa, T. Okajima
  In crystallo thermodynamic analysis of conformational change of the topaquinone cofactor in bacterial copper amine oxidase
  "Proc. Natl. Acad. Sci. U.S.A., 2019, 116(1), 135-140"
• E. Kinoshita‐Kikuta, H. Kusamoto, S. Ono, K. Akayama, Y. Eguchi, M. Igarashi, T. Okajima, R. Utsumi, E. Kinoshita, T. Koike
  Quantitative monitoring of His and Asp phosphorylation in a bacterial signaling system by using Phos-tag Magenta/Cyan fluorescent dyes.
  "Electrophoresis, 2019, 40(22), 3005-3013"
• 岡島俊英、五十嵐雅之、江口陽子、内海龍太郎
  多剤耐性細菌に有効な次世代型抗菌薬: 耐性細菌の出現しない抗菌薬の開発は可能か
  "化学と生物2019、57(7), 416-427"
• 村川武志，馬場清喜，岡島俊英
  銅含有アミン酸化酵素触媒反応におけるコンフォメーション変化のin crystallo熱力学解析
  生化学、2019、91(4): 565-571

総説

• Futai, M., Sun-Wada, G.H., Wada, Y., Matsumoto, N., and Nakanishi-Matsui, M.
  Vacuolar-type ATPase: A proton pump to lysosomal trafficking.
  Proc Jpn Acad Ser B Phys Biol Sci 95, 261-277 [link]
• 岡島俊英，五十嵐雅之，江口陽子，内海龍太郎
  多剤耐性細菌に有効な次世代型抗菌薬の開発
  化学と生物．57, 416-427 (2019) [link]

著書

▲ ページ上部へ

論文

• Jung J, Somiya M, Jeong SY, Choi EK, and Kuroda S.
  Low immunogenic bio-nanocapsule based on hepatitis B virus escape mutants.
  Nanomedicine. 14, 595?600(2018) [PubMed]
• Okamoto Y, Taguchi K, Yamasaki K, Sakuragi M, Kuroda S, Otagiri M.
  Albumin-Encapsulated Liposomes: A Novel Drug Delivery Carrier With Hydrophobic Drugs Encapsulated in the Inner Aqueous Core.
  J Pharm Sci. 107, 436-445(2018) [PubMed]
• 曽宮正晴、黒田俊一
  非カチオン性脂質ナノキャリアによる核酸医薬用DDS　第２編９章P75-P82　ドラッグデリバリーシステム-バイオ医薬品創成に向けた組織、細胞内、核内送達技術の開発-　
  CMC出版（東京）（2018）
• 曽宮正晴、黒田俊一
  B型肝炎ウイルス外皮Lタンパク質粒子を用いた感染機構解明および薬物送達　11章CSJカレントレビュー 生命機能にかかわる分子
  化学同人（京都）（2018）
• Li H, Tatematsu K, Somiya M, Iijima M, Kuroda S.
  Development of a macrophage-targeting and phagocytosis-inducing bio-nanocapsule-based nanocarrier for drug delivery.
  Acta Biomater. 73:412-423 (2018) [link]
• Matsuo H, Somiya M, Iijima M, Arakawa T, Kuroda S.
  CD11c-specific bio-nanocapsule enhances vaccine immunogenicity by targeting immune cells.
  J Nanobiotechnology. 16(1):59 (2018) [link]
• Liu Q, Somiya M, Iijima M, Tatematsu K, Kuroda S.
  A hepatitis B virus-derived human hepatic cell-specific heparin-binding peptide: identification and application to a drug delivery system.
  Biomater Sci. 7(1):322-335 (2018) [link]
• 立松健司、黒田俊一
  匂いの感じ方の個人差
  日本生物工学会誌（バイオメディア）(2018) V96 N11 p655
• Matsumoto, N., Sekiya, M., Tohyama, K., Ishiyama-Matsuura, E., Sun-Wada, G.H., Wada, Y., Futai, M., and Nakanishi-Matsui, M.
  Essential Role of the a3 Isoform of V-ATPase in Secretory Lysosome Trafficking via Rab7 Recruitment
  "Scientific Reports 8, 6701." [link]
• Sato, R., Kato, A., Chimura, T., Saitoh, S.I., Shibata, T., Murakami, Y., Fukui, R., Liu, K., Zhang, Y., Arii, J., et al.
  Combating herpesvirus encephalitis by potentiating a TLR3-mTORC2 axis
  "Nat Immunol 19, 1071-1082" [link]
• Takada H, Shiwa Y, Takino Y, Osaka N, Ueda S, Watanabe S, Chibazakura T, Suetsugu M, Utsumi R, and Yoshikawa H.
  Essentiality of WalRK for growth in Bacillus subtilis and its role during heat stress.
  "Microbiology. 164, 670-684 (2018)" [link]
• Hao Li, Kenji Tatematsu, Masaharu Somiya, Masumi Iijima, and Shun'ichi Kuroda
  Development of a Macrophage-Targeting and Phagocytosis-Inducing Bio-Nanocapsule-Based Nanocarrier for Drug Delivery
  "Acta Biomaterialia, 73, 412-423 (2018)" [link]
• 林将也, 岡田茜, 山本久美子, 奥河内知美, 日下知香, 工藤大蔵, 根本理子, 稲垣純子, 広瀬侑, 岡島俊英, 田村隆, 左右田健次, 稲垣賢二
  放線菌Streptomyces sp.590由来の抗腫瘍性酵素L‐メチオニン脱炭酸酵素の遺伝子クローニング,組換え発現,均一精製および性質検討
  "日本ビタミン学会誌、ビタミン, 92, 113-116(2018)" [link]

▲ ページ上部へ

総説

• 飯嶋益巳, 黒田俊一
  「ナノ界面における生体分子の精密整列固定化技術：バイオナノカプセル」
  農芸化学会誌. 化学と生物, 印刷中

▲ ページ上部へ

著書

• Tatematsu K, Kuroda S.
  Automated Single-cell Analysis and Isolation System: A Paradigm Shift in Cell Screening Methods for Bio-medicines.
  Single cell biomedicine, Series of translational bioinformatics, Springer-Nature Publishing (2018) in press
• 飯嶋益巳, 黒田俊一
  細胞・生体分子の固定化と機能発現（黒田章夫　監修）CMC出版（東京）第1編
  第13章　バイオナノカプセル足場分子を用いた抗体の精密整列固定化とバイオセンシング技術への応用
  印刷中
• 曽宮正晴、黒田俊一
  非カチオン性脂質ナノキャリアによる核酸医薬用DDS　第２編９章P75-P82　ドラッグデリバリーシステム-バイオ医薬品創成に向けた組織、細胞内、核内送達技術の開発-　
  CMC出版（東京）（2018）
• 曽宮正晴、黒田俊一
  B型肝炎ウイルス外皮Lタンパク質粒子を用いた感染機構解明および薬物送達　11章CSJカレントレビュー 生命機能にかかわる分子
  化学同人（京都）（2018）

▲ ページ上部へ

論文

• Eguchi Y, Okajima T, Tochio N, Inukai Y, Shimizu R, Ueda S, Shinya S, Kigawa T, Fukamizo T, Igarashi M, Utsumi R.
  Angucycline antibiotic waldiomycin recognizes common structural motif conserved in bacterial histidine kinases.
  J Antibiot (Tokyo). 70, 251-258 (2017) [PubMed]
• Hayashi M, Okada A, Yamamoto K, Okugochi T, Kusaka C, Kudou D, Nemoto M, Inagaki J, Hirose Y, Okajima T, Tamura T, Soda K, and Inagaki K.
  Gene cloning, recombinant expression, purification and characterization of l-methionine decarboxylase from Streptomyces sp. 590.
  J Biochem. 161, 389-398 (2017) [PubMed]
• Takahashi K, Mashima H, Miura K, Maeda D, Goto A, Goto T, Sun-Wada GH, Wada Y, Ohnishi H.
  Disruption of small GTPase Rab7 exacerbates the severity of acute pancreatitis in experimental mouse models.
  Scientific Reports. 7, 2817(2017) [PubMed]
• Soliman T, Yang SY, Yamazaki T, Jenke-Kodama H.
  Profiling soil microbial communities with next-generation sequencing: the influence of DNA kit selection and technician technical expertise.
  PeerJ. 5, e4178(2017) [PubMed]
• Kato A, Ueda S, Oshima T, Inukai Y, Okajima T, Igarashi M, Eguchi Y, Utsumi R.
  Characterization of H-box region mutants of WalK inert to the action of waldiomycin in Bacillus subtilis
  J Gen Appl Microbiol. 63, 212-221(2017) [PubMed]
• Kawamura R, Miyazaki M, Shimizu K, Matsumoto Y, Silberberg Y R, Sathuluri R R, Iijima M, Kuroda S, Iwata F, Kobayashi T, Nakamura C.
  A New Cell Separation Method Based on Antibody-Immobilized Nanoneedle Arrays for the Detection of Intracellular Markers.
  Nano Lett. 17, 7117-7124(2017) [PubMed]
• Li H, Onbe K, Liu Q, Iijima M, Tatematsu K, Seno M, Tada H, Kuroda S.
  Synthesis and assembly of Hepatitis B virus envelope protein-derived particles in Escherichia coli.
  Biochem Biophys Res Commun, 490, 155-160(2017) [PubMed]
• Somiya M, Yoshioka Y, and Ochiya T.
  Drug delivery application of extracellular vesicles; insight into production, drug loading, targeting, and pharmacokinetics.
  AIMS Bioeng, 4(1), 73?92(2017)
• Shin SH, Park SS, Choi J, Lee JH, Lee KJ, Ju EJ, Park J, Ko EJ, Park I, Jung J, Kuroda S, Hong SM, Hwang JJ, Lee JS Song SY, Jeong SY and Choi EK.
  Preclinical evaluation of cisplatin-incorporated bio-nanocapsule as chemo-radiotherapy for human hepatocellular carcinoma.
  Oncology Reports. 38, 2259-2266(2017) [PubMed]

▲ ページ上部へ

総説

• Iijima M, and Kuroda S.
  Scaffolds for oriented and close-packed immobilization of immunoglobulins
  Biosens Bioelectron. 89 (Pt 2), 810-821 (2017) [PubMed]
• 和田洋, 孫?和田戈虹, 川村暢幸
  哺乳類初期胚におけるミクロオートファジーによるシグナル制御
  実験医学. 35, 136-143(2017)
• 立松健司, 黒田俊一
  全自動１細胞解析単離装置 -開発経緯と応用事例-
  化学と生物. 55, 684-689(2017)
• 飯嶋益巳, 黒田俊一
  センシング分子の精密整列化技術
  ケミカルエンジニアリング，特集＝センシング技術の話題. 62(11), 1-7(785-791)(2017)
• Iijima M, Kuroda S.
  Innovative method for oriented and closed-packed immobilization of immunoglobulins.
  ATLAS of Science. October, 18(2017)
• Somiya M, Liu Q, and Kuroda S.
  Current Progress of Virus-mimicking Nanocarriers for Drug Delivery
  Nanotheranostics. 4, 415-429(2017) [PubMed]
• 曽宮正晴
  生物の仕組みに学ぶDDSナノキャリアの開発
  Drug Delivery System. 32, 156-157(2017)
• 黒田俊一
  アカデミア発DDS技術の起業化・事業化の課題
  Drug Delivery Systems. 32, 251-258(2017)

▲ ページ上部へ

著書

• Yoshimoto N, and Kuroda S.
  High-throughput analysis of mammalian receptor tyrosine kinase activation in yeast cells
  Methods in Molecular Biology. 1487, 35-52 (2017) [PubMed]
• 曽宮正晴, 黒田俊一
  最新DDS技術の先端バイオ医薬品への応用開発―ナノDDS、リポソーム、表面修飾、プロドラッグなどの最新技術と製剤への具体的応用― （2017） 技術情報協会
  第４章　核酸医薬品・遺伝子治療への応用を目的としたDDSの開発
  第７節　非カチオン性リポソームの核酸DDSへの応用
• 立松健司, 黒田俊一
  ナノメディシン・ナノプローブ（2017）キヤノン財団ライブラリ
  第２章　治療のためのドラッグキャリア
  第３節　バイオナノカプセル：ウイルスを模倣したドラッグデリバリーシステム
• 岡本一起
  ペプチド医薬品のスクリーニング・安定化・製剤化技術（2017）情報技術協会
  第１０章　第４節　副作用の少ないペプチド抗炎症薬の開発

論文

• Kawamura R, Shimizu K, Matsumoto Y, Yamagishi A, Silberberg Y.R, Iijima M, Kuroda S, Fukazawa K, Ishihara K, Nakamura C.
  High efficiency penetration of antibody?immobilized nanoneedle thorough plasma membrane for in situ detection of cytoskeletal proteins in living cells.
  Journal of Nanobiotechnology. 14, 74 (2016)
• Fujita K, Hiramatsu Y, Minematsu H, Somiya M, Kuroda S, Seno M, Hinuma S.
  Release of siRNA from liposomes induced by curcumin.
  Journal of Nanotechnology. 2016 (2016) 7051523
• Suzuki M, Yoshimoto N, Shimono K, Kuroda S.
  Deciphering the receptor repertoire encoding specific odorants by time-lapse single-cell array cytometry.
  Sci. Rep. 6, 19934 (2016) [PubMed]
• Yoshimoto N, Ikeda Y, Tatematsu K, Iijima M, Nakai T, Okajima T, Tanizawa K, Kuroda S.
  Cytokine-dependent activation of the JAK-STAT pathway in Saccharomyces cerevisiae.
  Biotechnol. Bioeng. 113, 1796-1804 (2016) [PubMed]
• Tatematsu K, Iijima M, Yoshimoto N, Nakai T, Okajima T, Kuroda S.
  Bio-nanocapsules displaying various immunoglobulins as an active targeting-based drug delivery system.
  Acta Biomaterialia. 35, 238-247 (2016) [PubMed]
• Iijima M, Yoshimoto N, Niimi T, Maturana AD, Kuroda S.
  Bio-nanocapsule-based scaffold improves the sensitivity and ligand-binding capacity of mammalian receptors on the sensor chip.
  Biotechnol. J. 11, 805-813 (2016) [PubMed]
• Liu Q, Somiya M, Shimada N, Sakamoto W, Yoshimoto N, Iijima M, Tatematsu K, Nakai T, Okajima T, Maruyama A, Kuroda S
  Mutational analysis of hepatitis B virus pre-S1 (9-24) fusogenic peptide.
  Biochem. Biophys. Res. Commun. 474, 406-412 (2016) [PubMed]
• Nakatani M, Ito J, Koyama R, Iijima M, Yoshimoto N, Niimi T, Kuroda S, Maturana AD
  Scaffold protein Enigma Homolog 1 overcomes the repression of myogenesis activation by Inhibitor of DNA binding 2.
  Biochem. Biophys. Res. Commun. 474, 413-420 (2016) [PubMed]
• Somiya M, Liu Q, Yoshimoto N, Iijima M, Tatematsu K, Nakai T, Okajima T, Kuroki K, Ueda K, and Kuroda S
  Cellular uptake of hepatitis B virus envelope L particles is independent of sodium taurocholate cotransporting polypeptide, but dependent on heparan sulfate proteoglycan.
  Virology. 497, 23-32 (2016) [PubMed]
• Ito J, Iijima M, Yoshimoto N, Niimi T, Kuroda S, and Maturana A
  RBM20 and RBM24 cooperatively promote the expression of short ENH splice variants.
  FEBS Lett. 590, 2262-2274 (2016) [PubMed]
• Takamatsu S, Shimomura M, Kamada Y, Maeda H, Sobajima T, Hikita H, Iijima M, Okamoto Y, Misaki R, Fujiyama K, Nagamori S, Kanai Y, Takehara T, Ueda K, Kuroda S, Miyoshi E
  Core-fucosylation plays a pivotal role in hepatitis B pseudo virus infection: a possible implication for HBV glyco-therapy.
  Glycobiology. 26, 1180-1189 (2016) [PubMed]
• Iijima M, Yoshimoto N, Niimi T, Maturana AD, Kuroda S
  Bio-nanocapsule-based scaffold improves the sensitivity and ligand-binding capacity of mammalian receptors on the sensor chip.
  Biotechnol. J. 11, 805-813 (2016) [PubMed]

▲ ページ上部へ

総説

• 良元伸男, 黒田俊一
  全自動１細胞解析単離装置および新たな細胞育種技術の開発
  バイオサイエンスとバイオインダストリー. 74, 30-33 (2016)
• 曽宮正晴, 黒田俊一
  非カチオン性リポソームによる核酸医薬送達法の可能性
  Drug Delivery Systems. 31, 35-43 (2016)
• 飯嶋益巳, 黒田俊一
  生体分子の整列固定化法
  日本生物工学会誌. 94(8), 497 (2016)
• 良元伸男, 黒田俊一
  特定の匂い分子に応答する嗅覚受容体群の網羅的取得法
  アロマリサーチ. 17(3), 41-45 (2016)
• Liu Q., Somiya M., and Kuroda S.
  Elucidation of the early infection machinery of hepatitis B virus by using bio-nanocapsule
  World J. Gastroenterol. 22, 8489-8496 (2016)
• 中井忠志, 谷澤克行, 岡島俊英
  ペプチドを分子内架橋する新規ラジカルSAM酵素
  生化学. 88(4), 506-510 (2016)
• 曽宮正晴, 黒田俊一
  バイオミミック技術による DDS ナノキャリアの開発：B型肝炎ウイルス感染機構に基づくバイオナノカプセルを中心に
  ファインケミカル. 45(11), 18-24 (2016)

▲ ページ上部へ

著書

• 良元伸男, 黒田俊一
  ヒトの感覚・知覚メカニズムと製品開発への活かし方（2016） 技術情報協会
  第４章　嗅覚・味覚のメカニズムと認知メカニズム
  第８節　匂いのデジタル信号化にむけた嗅細胞アレイセンサーの開発に向けて

論文

• Nakai T, Ito H, Kobayashi K, Takahashi Y, Hori H, Tsubaki M, Tanizawa K, Okajima T.
  The radical S-adenosyl-L-methionine enzyme QhpD catalyzes sequential formation of intra-protein sulfur-to-methylene carbon thioether bonds.
  J. Biol. Chem. 290, 11144-11166 (2015) [PubMed]
• Jung J, Jeong SY, Park SS, Shin SH, Ju EJ, Choi J, Park J, Lee JH, Kim I, Suh YA, Hwang JJ, Kuroda S, Lee JS, Song SY, Choi EK.
  A cisplatin?incorporated liposome that targets the epidermal growth factor receptor enhances radiotherapeutic efficacy without nephrotoxicity.
  Int. J. Oncol. 46, 1268-1274 (2015) [PubMed]
• Liu Q, Jung J, Somiya M, Iijima, M, Yoshimoto N, Niimi T, Maturana AD, Shin SH, Jeong SY, Choi EK, Kuroda S.
  Virosomes of hepatitis B virus envelope L proteins containing doxorubicin: synergistic enhancement of human liver-specific anti-tumor growth activity by radiotherapy.
  Int. J. Nanomed. 10, 4159-4172 (2015) [PubMed]
• Somiya M, Yamaguchi K, Liu Q, Niimi T, Maturana AD, Iijima M, Yoshimoto N, Kuroda S.
  One-step scalable preparation method for non-cationic liposomes with high siRNA content.
  Int. J. Pharm. 490, 316-323 (2015) [PubMed]
• Somiya M, Sasaki Y, Matsuzaki T, Liu Q, Iijima M, Yoshimoto N, Niimi T, Maturana AD, Kuroda S.
  Intracellular trafficking of bio-nanocapsule-liposome complex: identification of fusogenic activity in the pre-S1 region of hepatitis B virus surface antigen L protein.
  J. Control. Release. 212, 10-18 (2015) [PubMed]
• Murakawa T, Hamaguchi A, Nakanishi S, Kataoka M, Nakai T, Kawano Y, Yamaguchi H, Hayashi H, Tanizawa K, Okajima T.
  Probing the catalytic mechanism of copper amine oxidase from Arthrobacter globiformis with halide ions.
  J. Biol. Chem. 290, 23094-23109 (2015) [PubMed]
• Ito J, Iijima M, Yoshimoto N, Niimi T, Kuroda S, Maturana AD
  Scaffold protein enigma homolog activates CREB whereas a short splice variant prevents CREB activation in cardiomyocytes.
  Cell Signal. 27, 2425-2433 (2015) [PubMed]
• Takahashi K, Imai A, Iijima M, Yoshimoto N, Maturana AD, Kuroda S, Niimi T
  Mapping the heparin-binding site of the osteoinductive protein NELL1 by site-directed mutagenesis.
  FEBS Lett. 589, 4026-4032 (2015) [PubMed]

▲ ページ上部へ

総説

• 飯嶋益巳, 黒田俊一
  バイオナノカプセルを用いたセンシング分子整列化技術によるバイオセンシングの高感度化
  生物工学会誌. 93, 248-258 (2015)
• Somiya M, Kuroda S.
  Development of a Virus-mimicking Nanocarrier for Drug Delivery Systems: the Bio-nanocapsule
  Adv. Drug Deliv. Rev. 95, 77-89 (2015) [PubMed]

▲ ページ上部へ

著書

• 良元伸男, 黒田俊一
  第５章 １細胞育種を実現する全自動１細胞解析単離措置の開発
  ファインケミカルシリーズ 抗体医薬における細胞構築・培養・ダウンストリームのすべて（2015）（大政健史　監修）CMC出版（東京）. pp. 56-66
• 飯嶋益巳, 黒田俊一
  第４章 4.3 バイオナノカプセル
  DDSキャリア作製プロトコル集（2015）（丸山一雄　監修）CMC出版（東京）, pp. 118-129
• 曽宮正晴, 山口琴美, 黒田俊一
  バイオナノカプセル-リポソーム複合体（virosomes）のエンドソーム脱出機構の解明とsiRNAの細胞質送達技術への応用
  DDS研究の進歩 XXIV（奥直人, 山田静雄, 賀川義之, 板井茂, 並木徳之 編集）（2015）静岡DDS研究会（静岡）, pp. 75-80

論文

• Ihara M, Okajima T, Yamashita A, Oda T, Asano T, Matsui M, Sattelle DB, Matsuda K.
  Studies on an acetylcholine binding protein identify a basic residue in loop G on the β1 strand as a new structural determinant of neonicotinoid actions.
  Mol. Pharmacol. 86, 736-746 (2014) [PubMed]
• Ohno M, Otsuka M, Kishikawa T, Shibata C, Yoshikawa T, Takata A, Muroyama R, Kowatari N, Sato M, Kato N, Kuroda S, Koike K.
  Specific delivery of microRNA93 into HBV-replicating hepatocytes downregulates protein expression of liver cancer susceptible gene MICA.
  Oncotarget. 5, 5581-5590 (2014) [PubMed]
• Yoshimoto N, Tatematsu K, Iijima M, Niimi T, Maturana AD, Fujii I, Kondo A, Tanizawa K, Kuroda S.
  High-throughput de novo screening of receptor agonists with an automated single-cell analysis and isolation system.
  Sci. Rep. 4, 4242 (2014) [PubMed]
• Nakamura Y, Hasebe A, Takahashi K, Iijima M, Yoshimoto N, Maturana AD, Ting K, Kuroda S, Niimi T.
  Oligomerization-induced conformational change in the C-terminal region of Nel-like molecule 1 (NELL1) protein is necessary for the efficient mediation of murine MC3T3-E1 cell adhesion and spreading.
  J. Biol. Chem. 289, 9781-9794 (2014) [PubMed]
• Nakai T, Deguchi T, Frebort I, Tanizawa K, Okajima T.
  Identification of genes essential for the biogenesis of quinohemoprotein amine dehydrogenase.
  Biochemistry. 53, 895-907 (2014) [PubMed]
• Ninomiya K, Noda K, Ogino C, Kuroda S, Shimizu N.
  Enhanced OH radical generation by dual-frequency ultrasound with TiO₂ nanoparticles: Its application to targeted sonodynamic therapy
  Ultrason. Sonochem. 21, 289-294 (2014) [PubMed]

▲ ページ上部へ

総説

• 黒田俊一
  全自動１細胞解析単離装置（ASONECell Picking System）の開発
  BB Chubu, 5, 15-20 (2014)
• 黒田俊一
  ウイルス表面抗原タンパク質提示によるリポソームへの標的化能，細胞内侵入能，およびステルス能の付与
  膜, 39, 283-289 (2014)
• Yoshimoto N, Kuroda S.
  Single-cell-based breeding: rational strategy for the establishment of cell lines from a single cell with the most favorable properties.
  J. Biosci. Bioeng. 117, 394-400 (2014) [PubMed]

▲ ページ上部へ

著書

• 新美友章, 黒田俊一
  新分子・新材料によるメディカルエンジニアリング
  新規骨誘導タンパク質NELL1の発見から前臨床試験まで
  最先端メディカルエンジニアリング（名古屋大学最先端メディカルエンジニアリング編集委員会編）（2014）一粒書房
• 良元伸男, 黒田俊一
  新分子・新材料によるメディカルエンジニアリング
  バイオナノカプセルによる生体内ピンポイント薬物・遺伝子送達技術
  最先端メディカルエンジニアリング（名古屋大学最先端メディカルエンジニアリング編集委員会編）（2014）一粒書房
• 良元伸男, 黒田俊一
  第3章 ナノ・マイクロカプセルの応用例　第15節 診断
  ＤＤＳナノキャリア・バイオナノカプセルによるバイオイメージング
  ナノ・マイクロカプセル(状粒子)の調製・評価・応用≪検討例集≫（2014） 株式会社　技術情報協会

論文

• Murakawa T, Hayashi H, Sunami T, Kurihara K, Tamada T, Kuroki R, Suzuki M, Tanizawa K, Okajima T.
  High-resolution crystal structure of copper amine oxidase from Arthrobacter globiformis: assignment of bound diatomic molecules as O₂.
  Acta Crystallogr. D Biol. Crystallogr. 69, 2483-2494 (2013) [PubMed]
• Yoshimoto N, Kuroda S.
  Single-cell-based breeding: rational strategy for the establishment of cell lines from a single cell with the most favorable properties.
  J. Biosci. Bioeng. 117, 394-400 (2013) [PubMed]
• Miyata T, Tafuku S, Harakuni T, Tadano M, Yoshimoto N, Iijima M, Matsuo H, Matsuzaki G, Kuroda S, Arakawa T.
  A bio-nanocapsule containing envelope protein domain III of Japanese encephalitis virus protects mice against lethal Japanese encephalitis virus infection.
  Microbiol. Immunol. 57, 470-477 (2013) [PubMed]
• Iijima M, Yoshimoto N, Niimi T, Maturana AD, Kuroda S.
  Nanocapsule-based probe for evaluating the orientation of antibodies immobilized on a solid phase.
  Analyst. 138, 3470-3477 (2013) [PubMed]
• Miyata T, Tafuku S, Harakuni T, Tadano M, Yoshimoto N, Iijima M, Matsuo H, Matsuzaki G, Kuroda S, Arakawa T.
  A bio-nanocapsule containing envelope (E) protein domain III of Japanese encephalitis virus (JEV) protects mice against lethal JEV infection.
  Microbiol. Immunol. 57, 470-477 (2013) [PubMed]
• Iijima M, Yamamoto M, Yoshimoto N, Niimi T, Kuroda S.
  Bio-nanocapsules for signal enhancement of alkaline phosphatase-linked immunosorbent assays.
  Biosci. Biotechnol. Biochem. 77, 843-846 (2013) [PubMed]
• Yoshimoto N, Kida A, Jie X, Kurokawa M, Iijima M, Niimi T, Maturana AD, Nikaido I, Ueda HR, Tatematsu K, Tanizawa K, Kondo A, Fujii I, Kuroda S.
  An automated system for high-throughput single cell-based breeding.
  Sci. Rep. 3, 1191 (2013) [PubMed]
• Kida A, Iijima M, Niimi T, Maturana AD, Yoshimoto N, Kuroda S.
  Cell surface-fluorescence immunosorbent assay for real-time detection of hybridomas with efficient antibody secretion at the single-cell level.
  Anal. Chem. 85, 1753-1759 (2013) [PubMed]

▲ ページ上部へ

総説

• 飯嶋益巳, 黒田俊一
  バイオナノカプセルを用いるイムノセンシング分子の整列化技術
  バイオサイエンスとバイオインダストリー, 71, 314-317 (2013)
• 黒田俊一
  オール名古屋大学の純米酒「なごみ桜」
  日本醸造協会誌, 108, No.10 (2013)
• 曽宮正晴, 良元伸男, 黒田俊一
  バイオナノカプセル-リポソーム複合体の生体内ピンポイント薬剤送達への応用
  ファインケミカル, 42, 44-49 (2013)
• 松尾英典, 良元伸男, 黒田俊一
  バイオナノカプセルを用いた生体内ピンポイントDDS技術の開発
  表面, 50, 207-218 (2013)

▲ ページ上部へ

著書

• 良元伸男, 黒田俊一
  DDSの人体・環境・ものづくりへの適用技術（監修　中川晋作）（2013）　㈱NTS
  1-1-4-2 バイオナノカプセル, pp. 118-126

論文

• Iijima M, Somiya M, Yoshimoto N, Niimi T, Kuroda S.
  Nano-visualization of oriented-immobilized IgGs on immunosensors by high-speed atomic force microscopy.
  Sci. Rep. 2, 790 (2012) [PubMed]
• Matsuo H, Yoshimoto N, Iijima M, Niimi T, Jung J, Jeong SY, Choi EK, Sewaki T, Arakawa T, Kuroda S.
  Engineered hepatitis B virus surface antigen L protein particles for in vivo active targeting of splenic dendritic cells.
  Int. J. Nanomedicine. 7, 3341-3350 (2012) [PubMed]
• Shen J, James AW, Chung J, Lee K, Zhang JB, Ho S, Lee KS, Kim TM, Niimi T, Kuroda S, Ting K, Soo C.
  NELL-1 promotes cell adhesion and differentiation via Integrinβ1.
  J. Cell Biochem. 113, 3620-3628 (2012) [PubMed]
• Hasebe A, Nakamura Y, Tashima H, Takahashi K, Iijima M, Yoshimoto N, Ting K, Kuroda S, Niimi T.
  The C-terminal region of NELL1 mediates osteoblastic cell adhesion through integrin α3β1.
  FEBS Lett. 586, 2500-2506 (2012) [PubMed]
• Ishii J, Yoshimoto N, Tatematsu K, Kuroda S, Ogino C, Fukuda H, Kondo A.
  Cell wall trapping of autocrine peptides for human G-protein-coupled receptors on the yeast cell surface.
  PLoS One. 7, e37136 (2012) [PubMed]
• Somiya M, Yoshimoto N, Iijima M, Niimi T, Dewa T, Jung J, Kuroda S.
  Targeting of polyplex to human hepatic cells by bio-nanocapsules, hepatitis B virus surface antigen L protein particles.
  Bioorg. Med. Chem. 20, 3873-3879 (2012) [PubMed]
• Watanabe T, Igarashi M, Okajima T, Ishii E, Kino H, Hatano M, Sawa R, Umekita M, Kimura T, Okamoto S, Eguchi Y, Akamatsu Y, Utsumi R.
  Isolation and characterization of signermycin B, an antibiotic that targets the dimerization domain of histidine kinase WalK.
  Antimicrob. Agents Chemother. 56, 3657-3663 (2012) [PubMed]
• Xia J, Matsuhashi S, Hamajima H, Iwane S, Takahashi H, Eguchi Y, Mizuta T, Fujimoto K, Kuroda S, Ozaki I.
  The role of PKC isoforms in the inhibition of NF-κB activation by vitamin K2 in human hepatocellular carcinoma cells.
  J. Nutr. Biochem. 23, 1668-1675 (2012) [PubMed]
• Nakai T, Ono K, Kuroda S, Tanizawa K, Okajima T.
  An unusual subtilisin-like serine protease is essential for biogenesis of quinohemoprotein amine dehydrogenase.
  J. Biol. Chem. 287, 6530-6538 (2012) [PubMed]
• Yamada M, Oeda A, Jung J, Iijima M, Yoshimoto N, Niimi T, Jeong SY, Choi EK, Tanizawa K, Kuroda S.
  Hepatitis B virus envelope L protein-derived bio-nanocapsules: mechanisms of cellular attachment and entry into human hepatic cells.
  J. Control Release. 160, 322-329 (2012) [PubMed]
• Murakawa T, Hayashi H, Taki M, Yamamoto Y, Kawano Y, Tanizawa K, Okajima T.
  Structural insights into the substrate specificity of bacterial copper amine oxidase obtained by using irreversible inhibitors.
  J. Biochem. 151, 167-78 (2012) [PubMed]
• Hasebe A, Tashima H, Ide T, Iijima M, Yoshimoto N, Ting K, Kuroda S, Niimi T.
  Efficient production and characterization of recombinant human NELL1 protein in human embryonic kidney 293-F cells.
  Mol. Biotechnol. 51, 58-66 (2012) [PubMed]
• Ninomiya K, Ogino C, Oshima S, Sonoke S, Kuroda S, Shimizu N.
  Targeted sonodynamic therapy using protein-modified TiO₂ nanoparticles.
  Ultrason. Sonochem. 19, 607-614 (2012) [PubMed]

▲ ページ上部へ

総説

• 中井忠志
  キノヘムプロテイン・アミン脱水素酵素の生合成に必須の奇妙なプロテアーゼ
  生産と技術, 64, 37-39 (2012) [CiNii] [本文]
• 黒田俊一
  バイオナノカプセル（ウイルス感染機構を備えたナノキャリア）を用いる生体内ピンポイントＤＤＳの構築
  高分子, 61, 530-532 (2012) [CiNii]

▲ ページ上部へ

著書

• 黒田俊一（分担）
  第１５章　細胞工学
  工学系学生のための生化学　（左右田健次, 今中忠行, 谷澤克行　編集）（2012）㈱化学同人
• 黒田俊一（分担）
  第１４章　タンパク質工学
  工学系学生のための生化学　（左右田健次, 今中忠行, 谷澤克行　編集）（2012）㈱化学同人
• 良元伸男, 黒田俊一
  「先端バイオマテリアル」　5－3－9．中空タンパク質ナノカプセル（バイオナノカプセル）を用いる遺伝子・薬物のピンポイントDDS
  未来医療を支える先端バイオマテリアル～生体分子から有機・セラミック・金属まで～（監修 石原一彦, 秋吉一成, 山岡哲二）（2012）㈱NTS
• Yamada T, Jung J, Seno M, Kondo A, Ueda M, Tanizawa K, Kuroda S.
  Electroporation and use of hepatitis B virus envelope L proteins asbionanocapsules.
  Cold Spring Harb. Protoc. 2012, 702-705 (2012) [PubMed]