Our research in the area of regulatory bioorganic chemistry is focused on chemical biology and chemoinformatics using small molecules that bind to nucleic acids, and on the creation of small molecular compounds that bind to specific structures of DNA and RNA, control gene expression with these molecules, and create dream drugs to cure genetic diseases that cannot be cured. Specifically, we are developing small molecule ligands that specifically bind to target RNAs through compound design by organic synthesis, large-scale screening, and structure-activity relationship studies.